- "Machine learning-based lineage prediction from antimicrobial susceptibility testing phenotypes for Escherichia coli sequence type 131 clade C surveillance across infection types" Spoiler: the MDR ST131-C is pervasive in UTIs, underlying BSI trends. doi.org/10.1099/mgen... @microbiologysociety.orgJan 20, 2026 09:49
- This was a really fun study in collaboration with Theodor A. Ross and colleagues @uitnorgesarktiske.bsky.social @sfi-vi.bsky.social, training a model to predict the ST131-C genotype from antimicrobial susceptibility testing data, providing insight into its UTI prevalence and context for BSI trends.
- It's still largely infeasible for national genomic surveillance at the scale AST data is available (here 24,866 BSI and 28,639 UTI E. coli, 2006–2021), but combining existing 3254 BSI genomes and AST data allowed us to estimate the importance of this notorious MDR clone in Norwegian UTIs.
- And special thanks to Handal and Kaspersen et al. (doi.org/10.1093/jac/...) for sharing their AST data to serve as a UTI validation set for this genomic dataset.
