The timeline of co-transcriptional
#mRNA processing and
#modification may have to be revised: cleavage, termination, and
#m6A deposition may occur earlier than most
#splicing! Potential textbook changing study in bioRxiv by
edueyras.bsky.social & Rippei Hayashi labs!
www.biorxiv.org/content/10.1...
Single-molecule multimodal timing of in vivo mRNA synthesis
mRNA synthesis requires extensive pre-mRNA maturation, the organisation of which remains unclear. Here, we directly sequence pre-mRNA without metabolic labelling or amplification to resolve transcript...
