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  Akis (Argyris) Papantonis akispapantonis.bsky.social · Jan 21
  Preprint alert! 🥸 Yajie Zhu (PhD graduate) and Mariano Barbieri (postdoc, @spp2202.bsky.social Accelerator award) produced a package that will classify loops in your #3Dgenomics data based on (whichever) epigenomic data you have available. Keep reading... 1/n www.biorxiv.org/content/10.6...

  LoopBin – a VaDE-based neural network for chromatin loop classification

  Classifying chromatin loops from 3D genomics data according to their epigenetic and structural attributes is important for inferring their functional roles. Currently, such classification typically relies on the manual intersection of epigenomic signal peaks and loop anchor locations. To automate this, remove peak-calling biases and include information inherent to 3D genomics signal structure, we developed LoopBin, a framework based on a variational deep embedding (VaDE) neural network. We applied LoopBin to kilobase-resolution Micro-C data and segmented tens of thousands of loops into clusters with distinct features using minimal histone modification and transcription factor-binding data. These features were indicative of apparently distinct biological function by each subgroup of loops. Therefore, LoopBin can provide insights into the dynamic shifts in loop classification that can occur upon perturbation of cell homeostasis or signaling. ### Competing Interest Statement The authors have declared no competing interest.

  biorxiv.org
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  Dovetail Genomics dtgenomics.bsky.social · Nov 27, 2025
  🎥 Missed our latest “Ask the Experts” webinar? Watch it on demand! 👉 vimeo.com/1139356204 Part II of our 2025 ATE series explores HOW to integrate 3D genomics with other omics datasets — visualize, interpret & unlock deeper biological insights. #3DGenomics #MultiOmics #Webinar
  
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  Marc A. Marti-Renom mamartirenom.bsky.social · Nov 26, 2025
  Interested in #3DGenomics #4Dnucleome? Like #Barcelona? Would like to enjoy doing #science and to have fun during your #PhD? Apply now to La Caixa Foundation Doctoral #INPhINIT fellowships with us. DM or email in case of interest... 👇🏼👍🏼 lacaixafoundation.org/en/doctoral-... Please, repost... 🔄🙏🏼
  

  Doctoral INPhINIT fellowships - Incoming Call 2026

  We grant 30 fellowships for researchers of any nationality who wish to pursue a doctorate in a STEM discipline at research centres of excellence in Spain or Portugal.

  lacaixafoundation.org
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  Dovetail Genomics dtgenomics.bsky.social · Aug 5, 2025
  🔬 Researchers from UWA, AGRF, SCGH & Dovetail team used Micro-C to build the first 3D regulatory atlas of human osteoclasts — linking non-coding GWAS variants to gene targets and opening new paths for understanding bone disease like osteoporosis 🦴 🔗 doi.org/10.1093/jbmr... #3DGenomics #Multiomics
  
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  Dovetail Genomics dtgenomics.bsky.social · Jul 6, 2025
  We’re excited to exhibit at #GSA2025 in Auckland, NZ! Visit our booth to see how LinkPrep™ tech enables same-day, high-res chromatin interaction maps. Connect enhancers, silencers & more to gene targets. Integrates with ATAC-seq, ChIP-seq, RNA-seq & other omics data. #ChromatinTopology #3DGenomics
  
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  Jonas Paulsen jonnings.bsky.social · Jul 1, 2025
  🧬 New in Bioinformatics! We’re excited to share StripePy - a Python application for fast, robust detection of architectural stripes in Hi-C & Micro-C data. 🔗 Read the paper 👉 doi.org/10.1093/bioi... #3DGenomics #Bioinformatics #HiC #cool #hic @robomics.bsky.social @rea191.bsky.social

  StripePy: fast and robust characterization of architectural stripes

  AbstractMotivation. Architectural stripes in Hi-C and related data are crucial for gene regulation, development, and DNA repair. Despite their importance,

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