Yicheng Long
Assistant Professor of Biochemistry, Weill Cornell Medicine. www.longlab.org. Studying epigenetics, nucleic acids, stem cells and heart. Cech lab alumnus
- Reposted by Yicheng LongThe Reck-Peterson lab at Weill Cornell Medicine is seeking a technician or staff scientist to work on Aspergillus projects. Broad background in fungal biology and techniques required. Bioinformatics skills preferred. Find out more at: reckpetersonlab.org.
- Reposted by Yicheng LongWe are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22. biochem.weill.cornell.edu/join-our-fac...
- Our department at Weill Cornell is hiring a junior faculty member in the broad field of fundamental biomedical science. Please spread the word. Job ad here: www.nature.com/naturecareer...
- Reposted by Yicheng LongExcited to share our new study in @cp-devcell.bsky.social dissecting how the brain-associated transcription factor OTX2 drives anteriorization of the mammalian gut by enhancer remodeling using stem cell-based models. #development #enhancers #patterning #stemcells www.cell.com/developmenta...
- Reposted by Yicheng Long[Not loaded yet]
- Excited to share our work on the specificity of PRC2 subcomplexes in stem cell and differentiation. We show that PRC2.1 and PRC2.2 exhibit distinct H3K27 methylation specificity in human pluripotent stem cells and opposing role in differentiation. Now online at Mol Cell: www.cell.com/molecular-ce...
- Loss of PRC2.1 or PRC2.2 in hPSCs by separation-of-function mutants led to loss of H3K27me3 in a gene-specific manner. For example, the H3K27me3 peaks at BARHL1 and ARV1 are specifically deposited by PRC2.1 and PRC2.2, respectively. This specificity is observed genome wide.
- Reposted by Yicheng LongWe are excited to share our new preprint demonstrating that nucleic acid interactions with SUZ12 constrain PRC2 activity, establishing a kinetic buffer essential for targeted gene silencing and revealing vulnerabilities in diffuse midline gliomas. www.biorxiv.org/content/10.1...
