Let's get this site started. I'm excited to share that our work on transcription-coupled DNA repair is now published! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples lesion-stalled RNA Pol II to TFIIH. 🧬🐸
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cell.com/cell/fulltex...
STK19 positions TFIIH for cell-free transcription-coupled DNA repair
Together with structural analyses, a cell-free system for transcription-coupled nucleotide
excision repair (TC-NER) shows that STK19 is an integral component of the TC-NER complex
that couples RNA pol...
