We compared the most common approaches: Spatial Information (SI) and ANOVA-based tests, across 🐀 rat, 👩 human, and 💻 simulations. We found these methods emphasize distinct properties: SI highlights the contrast between peak and average firing. ANOVA emphasizes consistency across trials.

This methodological lens point us to biological patterns: 🐀 Rats showed a wide range of spatial responses. 👩 Humans showed weaker but consistent tuning. Importantly, these consistent responses overlap across species and may serve similar computational roles in flexible memory and generalization.