Viktoria Brunner
Bioinformatic Engineer interested in AMR diagnostics through WGS 🧬💊 | https://www.vbrunner.me 🌐 | PhD @ox.ac.uk @fowlerlab.org | MSc @ethz.ch
- Reposted by Viktoria BrunnerFor #WorldAntimicrobialAwarenessWeek, we introduce our recent paper on antibiotic-resistant subpopulations in TB. TB may be one of humanity’s oldest diseases, yet it still kills over 1M people yearly. As resistance spreads, knowing each patient’s resistance profile before treatment is vital. 🧬💊
- Reposted by Viktoria BrunnerDetecting minor resistance-associated variants in tuberculosis WGS samples improves the sensitivity of rifampicin resistance prediction: doi.org/10.1093/jaca... @philipwfowler.bsky.social @vbrunner.bsky.social #JACAMRNews #IDSky
- Our recent paper on rifampicin resistant subpopulations in M. tuberculosis (M. tb) has been published at JAC-antimicrobial resistance. I am really happy to see this work published just hours before submitting my DPhil thesis! 🔗👇 doi.org/10.1093/jaca...
- Key take-aways: 🚧 In this work, we show that conservative parameters in bioinformatic pipelines can obscure resistant subpopulations in clinical samples of M. tb.
- Reposted by Viktoria BrunnerCome and work with me and use the 53,897 samples of M. tuberculosis we have collated to help tackle this important disease! We are part of the OxCoD4TB consortium that is developing new therapeutics for tuberculosis. Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July bit.ly/4ndKOhF
- Reposted by Viktoria Brunner
- Thrilled to have returned to the Congress of @escmid.bsky.social this year in the beautiful city of Vienna, and to have had the opportunity to present my latest work on rifampicin-resistant subpopulations in M. tuberculosis. 📋 Find all the details in our preprint: 🔗👇 www.biorxiv.org/content/10.1...
- Reposted by Viktoria BrunnerAnother busy day at #ESCMIDGlobal! 0906 @vbrunner.bsky.social “RIF and subpopulations in TB” 0918 Ruan Spies “comparing TB pipelines" both in Hall 5 1000 Nicole Stoesser “plasmids & 1Health” in H2 1509 Jane Wei in Hall 2 “CAP and EHR” P1405 - Valentina Pennetta P2242 - Junko Takada
- 📢 Our preprint on rifampicin resistant subpopulations in clinical samples of M. tuberculosis has just been uploaded. We show how detection of resistant subpopulations can significantly improve WGS-based resistance prediction, and how they can help identify the source of resistance.
- Subpopulations in clinical samples of M. tuberculosis can give rise to rifampicin resistance and shed light on how resistance is acquired biorxiv.org/content/10.1101/202…
