Timothy P. Jenkins
I am an Associate Professor at DTU and leading the Digital Biotechnology Lab. I am passionate about harnessing the power of modern technology such as AI Protein Design to innovate the biotechnological landscape and develop real world solutions.
- 🧪🐍 AI vs venom! Our Nature paper with David Baker shows AI-designed proteins can block deadly snake toxins. Now featured by Reuters! 🎥 ✅ 80–100% survival in mice 💸 Cheap, fast, scalable 🌍 A step toward better antivenoms 📄 www.nature.com/articles/s41... 🎬 youtu.be/gnvEDMEr2mc
- Thrilled to announce our paper, "De novo-designed pMHC binders facilitate T cell-mediated cytotoxicity toward cancer cells," is officially out in @science.org! We used generative AI to build a 'GPS' for immune cells to hunt cancer. Read it here: doi.org/10.1126/scie...
- While I’m bouncing between emails and desperately waiting for my holiday, it’s good to know at least something in the lab is holding it together. Thermal stability might not be glamorous, but it’s underrated. Designerbodies: even when things get heated, still doing their job ;)
- At AffinityAI we’re moving from “finders keepers” to “designers binders”, one generative model at a time. If you could have a binder to anything, what would it be? (Proteins, obscure signalling pathways, that one reviewer who never gets back to you…;)
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- 🎧 Had the pleasure of joining Anders Høeg Nissen on the AI Denmark Podcast to talk about how we’re using AI to crack the protein code 🧬 Catch my segment from 9:30 (and yes — it’s in English 😉) 🎙️ open.spotify.com/episode/4g3R...
- Great to see #AffinityAI represented by Esperanza and Oliver at the DTU Startup Day 💪 Lots of interest in what we’re building, especially the fact that we deliver #real #reagents rather than just #AI predictions. Excited for what's to come!
- 🚨 We’re hiring a PhD student! 🚨 Join us at DTU Bioengineering + collaborators Messoud & Håkan Ashina + Esperanza Rivera de Torre to bring preventative migraine therapeutics from 💻 to 🧠 🔗 Apply: lnkd.in/dCRU_EN3 🔍 Project: lnkd.in/dbpi8MwX
- 🚨 Big news! We’ve received a NovoNordisk Foundation Tandem Grant for #MIGRAINE — designing #AI-powered #GPCR-targeting biologics for chronic migraine. From computer to human in 4 years. Proud to team up with Messoud and Hakan Ashina, as well as Esperanza Rivera de Torre! 🧠 + 💊 + 🧬 = new hope.
- 🚀 Big news: AffinityAI is live We’ve built a platform for custom protein binders, AI-designed, in vitro validated, and entirely animal-free. I'm proud to lead this as CEO. 🔗 affinityai.org #AffinityAI #Biotech #ProteinEngineering
- 1/ 🚀 InstaNovo just got a major upgrade. Our Nature Machine Intelligence paper with @instadeepai presents v0.1—but while the paper was under review, we kept building. Now releasing InstaNovo v1.1, with major gains. Blog: bit.ly/4lircYB 🧵
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- 🎉 Big news! Our paper is out in Nature Machine Intelligence! "InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments" 🔗 www.nature.com/articles/s42... 👇 Thread 🧵
- We developed InstaNovo & InstaNovo+, combining transformers 🧠 with diffusion models 🔁 to solve one of proteomics' hardest problems: 🚫 No genome? No problem. ✅ De novo sequencing from raw spectra — fast & accurate.
- 🚀 Tackling one of life science’s biggest challenges: AI-driven biologics design! Excited to lead #DTU’s collaboration with #NovoNordisk to build a closed-loop #AI platform for binder design & optimization. Even better? We’re hiring! 📢 6 open positions! 🎉 (1/5)
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