David Vilchez

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  David Vilchez thevilchezlab.bsky.social · Feb 5
  Our new review on proteostasis of organelles in aging & disease is now online in The FEBS Journal! We discuss recent insights on how #proteostasis safeguards organelle integrity and function across the cell in #aging and disease doi.org/10.1111/febs...
  

  FEBS Press

  Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the n....

  doi.org
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  David Vilchez thevilchezlab.bsky.social · Feb 5
  The review covers proteostasis mechanisms across major organelles, including: • Nucleus • Mitochondria • Endoplasmic reticulum • Golgi apparatus • Lysosomes We also highlight proteostasis in membraneless organelles, such as: • Stress granules • Processing bodies • Nucleolus • Nuclear speckles
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  David Vilchez thevilchezlab.bsky.social · Feb 5
  Great collaborative effort by: Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu @cecad.bsky.social @unicologne.bsky.social @uniklinikkoeln.bsky.social
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