Pranay Sinha
ID doc, TB researcher, writer, husband, and dog parent. Assistant Professor at Boston University.
- Everyone in TB talks about “nutrition matters.” But what happens when you actually ask households with TB what kind of nutritional support works for them? We did exactly that through the TB LENS qualitative study in South India. tinyurl.com/mr42k9k8
- TB LENS is nested within TB LION, which provided full daily nutritional requirements (rice, pulses, groundnuts, oil + multivitamins) to undernourished household contacts for six months. 2600 Kcal daily 82g of protein We interviewed HHCs, health workers, and nutritionists about the experience.
- The verdict? People loved the intervention. Participants reported: • weight gain • more energy • better mobility • fewer skipped meals • less financial stress
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- Reposted by Pranay Sinha“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...
- Reposted by Pranay SinhaU.S. aid cuts and withdrawal from WHO are a terrible blow for global health, but also an opportunity for the European Union to step up as a superpower: Together, EU member states spend nearly twice as much as America on ODA.
- The House just proposed slashing NIH funding by more than a third. I wrote about what this means—not just for science, but for America’s health, economy, and future. 🧵👇 ps7uy.substack.com/p/we-lead-th...
- 1/ The House just proposed slashing NIH funding from $42B to $27.5B. A cut this deep wouldn’t just hurt—it would uproot American biomedical innovation. As a physician-scientist whose career depends on NIH funding, I can tell you: The panic is real.
- 2/ The NIH isn’t some bloated bureaucracy. It’s the engine of American discovery. Founded in 1930, it’s supported nearly a century of breakthroughs—from chemotherapy to mRNA vaccines.
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View full thread14/ The Senate can still stop this. And doctors-turned-senators like Cassidy, Marshall, Barrasso, Tillis, and Paul know: Every cure starts with a question. Let’s not make the next generation of questions go unanswered.
- Reposted by Pranay SinhaAn advance look at “On Parade,” David Plunkert’s cover for next week's issue. #NewYorkerCovers
- We know that undernourished persons with TB are at higher risk of mortality, but why? My incredible mentee Dr. Alexa Tabackman tries to understand why in this new paper: tinyurl.com/2jc76v8c A thread 🧵 @buceid.bsky.social @bostonmedical.bsky.social @madhupai.bsky.social @meganmurray.bsky.social
- 2/10) We conducted a multicenter prospective cohort analysis with 1587 pulmonary TB patients from 5 diverse sites across India (2015-2019). Our primary exposure was premorbid BMI <17 kg/m² (moderate-severe undernutrition). @theunion.org @richardwhite321.bsky.social @who.int
- (3/10) Why focus on premorbid BMI? Weight loss commonly occurs due to TB itself. Evaluating BMI before symptom onset helps clarify the true role of undernutrition in driving disease severity.
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View full threadThank you to our funders for their extraordinary support. @niaidnews.bsky.social @bwfund.bsky.social @icmr.bsky.social Indian Department of Biotechnology Warren Alpert Foundation
- Reposted by Pranay SinhaI get why this view is attractive to people—it gives them a false sense of control. But in reality, we can’t really control whether we get MS, cancer, etc. Even non-smokers get lung cancer. People who do not have obesity get diabetes. Better to seek evidence-based treatments than live in delusion.
- Reposted by Pranay SinhaTo be clear, if this bill passes, it will end all scientific research & medical training in the US. It will close hospitals. It will be economically devastating. Millions will lose their jobs. Call your representatives & tell them to vote fuck no on 15% IDC rates & the rest of this horror show.
- Reposted by Pranay SinhaThere’s no amount of diet and exercise that will prevent things like cancer and autoimmune diseases. Obviously the choices we make do matter to some extent, but wellness influencers are selling is an illusion of control that’s maliciously deceptive and harmful.
- Reposted by Pranay Sinha“Measles vaccine is one of the best tools we have to protect public health. Like all medicines, there can be a risk of side effects, but the benefits far outweigh them: both for individuals and the community as a whole” ourworldindata.org/measles-vacc...
- Reposted by Pranay SinhaMeasles Cases Top 1,000: A Crisis of Complacency www.medpagetoday.com/opinion/seco...
- Reposted by Pranay SinhaOur database of terminated grants is powered first by PIs who send us information about their grants. If your grant was terminated--or if you received a stop work order of some sort--let us know! forms.gle/8qWNSjBerJ1G...
- Want to know more about the gory detail of NIH cuts and how they are impacting your home towns, your states? @noamross.net and @scott-delaney.bsky.social have put it all together for you. 6/ airtable.com/appjhyo9NTvJ...
- Reposted by Pranay SinhaGuidance on MMR in context of outbreaks.
- It’s about time we take intelligence seriously. Kudos to the administration for stepping up surveillance on… <checks notes> …Greenland? www.wsj.com/world/greenl...
- Reposted by Pranay SinhaHealthcare Infection Control Practices Advisory Committee (HICPAC) becomes latest casualty of Trump regime They were close to finalizing guidelines for airborne infection control in hospitals, including the use of N95 masks Measles is spreading, Covid isn’t over & hospitals just got more dangerous
- Reposted by Pranay SinhaLinda McMahon wrote Harvard a letter to which they responded by noting areas that are in need of corrections and then posted it on social media. Great job Harvard!👏👏👏
- Reposted by Pranay SinhaInsane is exactly the phrase I would have used! ‘This is insane:’ New NIH policy on funding foreign scientists stirs outrage www.science.org/content/arti...
- Reposted by Pranay SinhaFormer Weather Service Leaders Warn Staffing Cuts Could Lead to ‘Loss of Life’ - The New York Times www.nytimes.com/2025/05/02/w...
- Reposted by Pranay SinhaPresident Trump's proposed 2026 budget is just another example of this administration taking a chainsaw to our nation’s health system. Read our full statement from Executive Director @awright2care.bsky.social: familiesusa.org/press-releas...
- Reposted by Pranay SinhaI am extremely pleased to share this feature articulating why I have lost my sanity lately. www.science.org/content/arti...
- Reposted by Pranay SinhaA Perspective in Nature presents a transparent and reproducible scientific framework to formalize how trillions in economic losses are attributable to the extreme heat caused by emissions from fossil fuel companies, which could inform climate liability claims. go.nature.com/4jOubX8 🧪
