The group of Heinz Koeppl
@tuda.bsky.social shows the tuning of ultrasensitivity in genetic logic gates using antisense RNA feedback. Check out the paper in ACS Synthetic Biology:
pubs.acs.org/doi/10.1021/...
Tuning Ultrasensitivity in Genetic Logic Gates Using Antisense RNA Feedback
Inverting genetic logic gates fueled by transcriptional repression is an established building block in genetic circuit design. Often, the gates’ dose–response curves require large changes in dose to t...
