Sean Flynn
Enhancers and 3D genome structure | Lecturer @uniofexeter.bsky.social | sites.google.com/view/flynnlab/
- Lots of exciting PhD projects available through @swbiodtp.bsky.social If you are interested in our project using stem cells, CRISPR and genomics, please get in touch. Informal inquiries encouraged Project: www.swbio.ac.uk/files/2025/1...
- We have just launched our projects for #phd studentships starting in Sept 26 🙌 ⏰Application deadline: Midday, Wed 3 Dec 25 Come and see the (wide!) range of #bioscience projects 👉 tinyurl.com/3m9um286
- Exciting postdoc opportunity!
- Reposted by Sean FlynnWe are hiring! We are looking for a PDRA to study the epigenetics of breast cancer dormancy using chemical biology and genomics approaches. This is a 3-year position and is aimed at chemical biologists or biologists. Please share and apply using the link below 👇👇👇 www.imperial.ac.uk/jobs/search-...
- Reposted by Sean FlynnCheck it out, Chromatin Kids! Chromatin remodeller does stuff to Transcription Factors! Functions where it is seldom seen! Both decreases and increases chromatin accessibility! How cool is that?
- The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers biorxiv.org/content/10.1101/202…
- Please share! PhD projects available through @gw4biomeddtp.bsky.social Please get in touch if you are interested in studying chromatin biology in stem cell models gw4biomed.ac.uk/architects-o... gw4biomed.ac.uk/risk-vs-prot... gw4biomed.ac.uk/rna-dependen... gw4biomed.ac.uk/investigatin...
- Reposted by Sean FlynnModel organism communities are fantastic. Good work, "Drosophilists"! www.nature.com/articles/d41...
- Reposted by Sean FlynnHow does (local #DNA) structure affect (3D #genome) structure? Can mutating G4s abolish #enhancers key for #blood function? In the second part of our explorations of #G4s in gene regulation, we show how abolishing G-quadruplex structures in the genome disrupts enhancers. 1/9 doi.org/10.1186/s130...
- Reposted by Sean FlynnHappy to be part of this exciting work. A must-read for enhancer aficionados: A massive effort has gone into generating genome-wide STARRseq in hPSCs and conducting functional validation assays. Congratulations to all authors, Stefan and Ufuk, for leading this project 🎉.
- Delighted & excited to share our latest preprint on non-canonical enhancers in human pluripotent stem cells, the result of a fantastic and fun collaboration with @guenesdoganlab.bsky.social: www.biorxiv.org/content/10.1... 🧵 below
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- Reposted by Sean FlynnWe are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today! Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters! allirelandchromatinconsortium.ie/annual-meeti...
- We have a funded PhD position available in Exeter @exeter.ac.uk Gene Regulation in Brain Development and Disease 🧬 Please share / repost www.exeter.ac.uk/study/fundin...
- Reposted by Sean Flynnjobs.exeter.ac.uk/hrpr_webrecr... Interested in data management? Want a permanent position working in beautiful Devon and work collaboratively to support the work of lots of genomics team? Apply!!
- If you are interested in #Epigenetics apply for a PhD with Jack Hardwick and Jonathan Hanley in Bristol, and our group in Exeter. Elucidating the role of DNA modifications in neurons Funded by #SWBio DTP Deadline: Dec 4 To apply: www.swbio.ac.uk/programme/ho...
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- Reposted by Sean FlynnFully funded #PhD Studentship with myself and JJ Phillips at the Living Systems Institute, @uniofexeter.bsky.social "Control of chromatin remodeller activity to direct cell fate decisions" #Chromatin #Transcription #StemCells #StructuralBiology Please re-skeet! www.exeter.ac.uk/research/ins...
