Sebastian Deorowicz

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  Sebastian Deorowicz sdeorowicz.bsky.social · Dec 23, 2025
  MDCompress (www.biorxiv.org/content/10.6...) is our recent proposal for storing molecular dynamics simulations. Try if you feel that your XTC files are too big or need random access features. Great collaboration with Travis Wheeler's lab.
  

  MDCompress: better, faster compression of molecular dynamics simulation trajectories

  Motivation: Molecular dynamics (MD) simulations model the physical movements of atoms in biomolecular systems over time, providing atomic-resolution insight into conformational changes, binding events...

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  Sebastian Deorowicz sdeorowicz.bsky.social · Jul 19, 2025
  Interested in a tool that aligns millions of proteins in minutes with quality similar to or better than the state-of-the-art utilities? Please take a look at our FAMSA2 paper: www.biorxiv.org/content/10.1... and GH repo: github.com/refresh-bio/...
  

  FAMSA2 enables accurate multiple sequence alignment at protein-universe scale

  We introduce FAMSA2, an algorithm that produces high-accuracy multiple protein sequence alignments with unprecedented speed. Across structural, phylogenetic, and functional benchmarks, FAMSA2 matches ...

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• Reposted by Sebastian Deorowicz
  
  Nature Methods natmethods.nature.com · May 15, 2025
  Vclust generates fast and accurate estimation of average nucleotide identity (ANI) for viral genomes, scaling clustering to millions of genomes. @sdeorowicz.bsky.social @bedutilh.bsky.social @prozwalak.bsky.social @uni-jena.de @microverse.bsky.social www.nature.com/articles/s41...
  
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