An intranasal flu antibody can protect against both influenza A and B in mice and nonhuman primates and is safe in humans, according to new preclinical experiments and two phase one clinical trials published in
#ScienceTranslationalMedicine.
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Phase 1 and preclinical studies reveal safety, pharmacokinetics, and efficacy of intranasal delivery of the influenza antibody CR9114
Intranasal CR9114 is safe in humans, and twice-daily dosing confers protection against influenza virus challenge in macaques.
