Anubhav Prakash
Some sort of experimental biologist interested in shapes and patterns. Postdoc @mpi-muenster; earlier @ashoka university. Once a grad student @NCBS Bangalore
- Reposted by Anubhav PrakashThe cell cortex behaves like a sorting hat: it groups membrane proteins by how tightly they bind to dynamic actin. 🪄🎩 Insightful post from Teodora Piskova covering recent work of the #MayorLab & team @ncbsbangalore.bsky.social #CellBio #preprint #preLight ⬇️ prelights.biologists.com/highlights/a...
- Bhaval discusses our work to give an exploratory view on the forces driving epithelial diversity. Check it out!
- From uniform beginnings, junctional heterogeneity and cell-specific mechanics choreograph the stunning diversity of sensory epithelia. Bhaval Parmar discusses recent work from Anubhav Prakash @prakash-patterns.bsky.social & colleagues. #DevBio #preLight ⬇️ prelights.biologists.com/highlights/j...
- This image here shows a 3D-rendered cristae from the mouse's inner ear. In red ♥️ is F-actin marking cell junctions and the 💙 is beta-Spectrin 2 marking the mechano-sensory hair cells. These are important for the sense of balance and linear acceleration.
- Reposted by Anubhav PrakashBoris Shraiman points a physicist’s eye on biological quandaries news.ucsb.edu/2025/022264/... 🧪
- My favourite gene, Vangl2 in action
- On how Vangl2 shapes the heart❤️ Planar cell polarity protein, Vangl2, goes out of its way to shape the heart through a planar polarity-independent mechanism. #preprint from the team of @meilhacsigolene.bsky.social #preLight by @prakash-patterns.bsky.social⬇️ prelights.biologists.com/highlights/v...
- Reposted by Anubhav PrakashExcited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!
- 🚀 Exciting news! ERC Synergy Grant of €8.5 million to Sara Wickström @sarawickstrom.bsky.social, Daniel St Jonston @gurdoninstitute.bsky.social and Ewa Paluch @universitypress.cambridge.org! This highly interdisciplinary project will boost our understanding of tissue biology. #ERCSyG @erc.europa.eu
- Ever wondered how tissues have diverse organisations? We did with some experiments on sensory epithelia of 🐣 🐟 and 🐁. We found that these epithelia are initially very similar. As they develop, cell types acquire a solid/fluid-like mechanical state driving the cellular organisation. Comments welcome!
- Junctional Heterogeneity Shapes Epithelial Morphospace biorxiv.org/content/10.1101/202…
- Thanks a lot to co-authors for their contribution and Raj Ladher @earlab.bsky.social for his guidance. @ncbsbangalore.bsky.social and Ashoka University for the support.
- Reposted by Anubhav Prakash#authorinterview Anubhav Prakash @prakash-patterns.bsky.social from Prof Raj Ladher lab earlab.bsky.social at NCBS, Bangalore talks about his work on "Kompartment Konnection: How the Cochlea Coordinates for a Perfect Design" PLOS Biology biopatrika.com/academia/res... @ncbsbangalore.bsky.social
- link.growkudos.com/1efpeb7d8n4 A short article is now available at Kudos on our work @earlab.bsky.social at @ncbsbangalore.bsky.social about how the cochlea generates its pattern.
- The ear's organ of Corti as a model system of how developmental instructions coordinate across spatial scales so that tissues are sculpted reproducibly 📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org ➡️ bpod.org.uk/archive/2025...
- Reposted by Anubhav PrakashMy lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
- Editor's insightful commentary on our work in cochlear morphogenesis.
- #Morphogens cooperate to guide development of the #cochlea. This Primer explores a @plosbiology.org study showing how #PlanarCellPolarity of individual cells is integrated across distinct regional compartments to ensure proper organ #morphogenesis. Paper: plos.io/4nmD8IW Primer: plos.io/3IjPkLR
- Reposted by Anubhav PrakashOur September issue is online! www.embopress.org/toc/17574684... On the cover: AAV-mediated delivery of Clic5 restores inner ear structure & function in a model of hereditary hearing and balance loss 👉 doi.org/10.1038/s443... Scientific image: R. Hahn & K. Avraham, at Tel Aviv University
- We show the Organ of Corti is composed of adhesion-molecule based compartments and the interaction between these compartments (compartment coupling) drives pattern and polarity. This seems like a fundamental design principle of developing tissues.
- How does the #cochlea achieve its spiral shape? @prakash-patterns.bsky.social @earlab.bsky.social &co show that the expression of adhesion & polarity proteins pattern the #OrganOfCorti and drive the compartment-specific organisation to achieve the cochlea spiral @plosbiology.org 🧪 plos.io/4nmD8IW
- It was an adventurous quest. Aptly supported by @earlab.bsky.social @ncbsbangalore.bsky.social and Ashoka University. A big thanks to Sukanya, @ramankaushik.bsky.social, Pallavi and Anton for their contribution. Write to us for any query/know more!
- Reposted by Anubhav Prakash#LatestPublication In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell. 🎉Congratulations to the team! journals.plos.org/plosgenetics...
- preprint: Using a combination of experiments and theory, we show that force patterning at apical junctions drives three-dimensional spatial organisation in multi-cell-type epithelia. Give us your comments!
- Force patterning drives cell flows and 3D spatial order in auditory epithelia biorxiv.org/content/10.1101/202…
- It was wonderful working with Julian, Sukanya, @earlab.bsky.social , Madan and Karsten. A big thanks to Ashoka University and @ncbsbangalore.bsky.social for their support.
- Reposted by Anubhav Prakash#authorinterview Anubhav Prakash @prakash-patterns.bsky.social from Prof Raj Ladher lab @earlab.bsky.social, NCBS @ncbsbangalore.bsky.social talks about his work on "Pushing and pulling cells from chaos to order" biopatrika.com/academia/res... @natcomms.nature.com
- Reposted by Anubhav Prakash#LatestPublication in @natcomms.nature.com by Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea. 🎉Congratulations to the team! @prakash-patterns.bsky.social @earlab.bsky.social Read here: www.nature.com/articles/s41...
