Bacteria encode homologs of the human NACHT proteins that form inflammasomes and use them to defend against phage
#infection.
@amyconte.bsky.social @aaronwhiteley.bsky.social &co show that bNACHT25 detects diverse phages indirectly through interaction with the host chaperone DnaJ. 🧪
plos.io/4koXP60
DnaJ mediates phage sensing by the bacterial NLR-related protein bNACHT25
Bacteria encode homologs of the human NACHT proteins that form inflammasomes, and use them to defend against phage infection. This study shows that the NLR-related protein bNACHT25 detects diverse pha...
