Philippa Matthews
Prof of Infectious Diseases working across continents & disciplines.
#HBV #hepatitis research
@Crick.ac.uk @UCL.ac.uk @uclh.bsky.social
crick.ac.uk/research/labs/phili…
🦠🧬🧪🩺🌍🇿🇦🇰🇪🇺🇬🇪🇺
#globalhealth #NHS #IDSky #MedSky #HepSky #European
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- A protocol for 'MoLo' #liver #health project for the #Mongolian community in #London is now on line: a template for combining #education, healthcare & #research. wellcomeopenresearch.org/articles/11-72 #HBV #HIV #LiverSky #IDSky #MedSky 🧪 @crick.ac.uk @uclnews.bsky.social @emilymartyn.bsky.social
- Our #liver #health project ‘MoLo’ for the #Mongolian Community in #London: #education, assessment for #diabetes, metabolic liver disease #MASLD, #HIV & viral #hepatitis, & linkage to care. Huge team effort with brilliant engagement. @who.int @crick.ac.uk @ucl.ac.uk #HBV #HCV #LiverSky #MedSky 🧪🇲🇳
- Our preprint addresses therapeutic drug monitoring for #HBV #hepatitisB. It may sound niche, but is a huge clinical & research gap. Better understanding could inform better #treatment & improve outcomes. 🧪💊 #LiverSky #MedSky #IDSky #Pharmacology #TDM #tenofovir www.researchsquare.com/article/rs-8...
- Our #liver #health project ‘MoLo’ for the #Mongolian Community in #London: #education, assessment for #diabetes, metabolic liver disease #MASLD, #HIV & viral #hepatitis, & linkage to care. Huge team effort with brilliant engagement. @who.int @crick.ac.uk @ucl.ac.uk #HBV #HCV #LiverSky #MedSky 🧪🇲🇳
- A #trial that involves withdrawing a lifesaving #vaccine (backed by decades of safety data) in a low income, high prevalence setting? Over 1000 new #HBV infections predicted as a result. Flawed endpoints. No ethics oversight. Exploitative, corrupt malpractice. #LiverSky #MedSky #CDC @gavi.org 🧪
- We have the CDC-funded Hepatitis Vaccine trial in Guinea-Bissau protocol. It’s worse than you thought. Check it out, first in Inside Medicine… with @pauloffit.bsky.social David Boulware and others. insidemedicine.substack.com/p/scoop-the-...
- The #preprint movement has changed the academic ecosystem for the better: wider dissemination, community review, democratisation of access. Brave, disruptive & pioneering 🙌🏽🧪 Thank you @richardsever.bsky.social @johninglis.bsky.social @biorxivpreprint.bsky.social @medrxivpreprint.bsky.social
- Terrific origin story, history, and future of bioRxiv and medRxiv by @richardsever.bsky.social in @mbio.bsky.social journals.asm.org/doi/10.1128/...
- Interesting to see this from #GSK... but lots of questions that still need answering (especially 'please can we see the data?'). Noting functional cure is still attained for a minority with #Bepi, and only when taken on top of standard of care #therapy with NA agents. #MedSky #LiverSky #HBV #NoHep 🧪
- We describe #HBV infection in #Uganda, to determine #treatment eligibility. #Liver assessment by #fibroscan important to determine who should be treated. Some drug resistance motifs seen in the context of #HIV. @who.int @crick.ac.uk @ndm.ox.ac.uk #LSHTM #UVRI #MedSky 🇺🇬 🧪 doi.org/10.1016/j.ji...
- Strengthening clinical, translational, implementation #research in #Africa for the #elimination of viral #hepatitis is an urgent #PublicHealth priority. We have the tools, but the field has been neglected. 🧪 #HBV #MedSky @lancetmicrobe.bsky.social @who.int www.sciencedirect.com/science/arti...
- #HepatitisC #HCV has been neglected in #Africa but affordable pangenotypic #DAA #treatment, community engagement & #decentralisation offer improved prospects. We report a #microelimination programme in #Uganda. @ndm.ox.ac.uk @crick.ac.uk @who.int 🧪🇺🇬🌍💊 #MedSky www.sciencedirect.com/science/arti...
- Dangerous retrograde step as #US #CDC pulls back on recommendations for #HBV #vaccine at #birth & dilutes advice for a proper three dose #immunisation schedule. This is a safe, cheap, robust & well-evidenced vaccine. There is no evidence of harm. 🧪 @who.int @gavi.org www.bbc.co.uk/news/article...
- It’s a crucial moment to say this again, loudly: #vaccines cause adults. Let’s keep causing adults. 🧪 #HBV #NoHep #vaccineswork #MedSky #HepSky #IDSky #PublicHealth @who.int @gavi.org @altcdc.altgov.info @worldhepalliance.bsky.social
- If timely birth dose #HBV #vaccine is restricted, there will be a predictable surge in new chronic infections. There are *no* documented harms of this vaccine dose in early life. In contrast, chronic viral #hepatitis leads to *over a million deaths a year worldwide*. #vaccineswork #MedSky 🧪💉
- Thanks @kevinmckenna.co.uk for inspiring reflections on #HIV… views from the coal face of lived experience, healthcare delivery & politics… a potent cocktail! We need more voices, commitment to ongoing advocacy, & funding for #research & #implementation. #WorldAIDSDay @crick.ac.uk @england.nhs.uk 🧪
- Congratulations to the Bishop group @crick.ac.uk for an inspiring #WorldAIDSDay event this week. Personal stories, #stigma, #treatment, #PrEP, #healthcare, wellbeing, #ageing, #research & partnerships… a mosaic of reflections. We have achieved a lot, but more still to be done. #HIV #MedSky #IDSky 🧪
- Congratulations to the Bishop group @crick.ac.uk for an inspiring #WorldAIDSDay event this week. Personal stories, #stigma, #treatment, #PrEP, #healthcare, wellbeing, #ageing, #research & partnerships… a mosaic of reflections. We have achieved a lot, but more still to be done. #HIV #MedSky #IDSky 🧪
- #UKHSA report published today. www.gov.uk/government/p... Progress is being made towards ambitious high-profile @who.int goals for the #elimination of #HepatitisB as a public health threat... but we need to reflect on the challenges still ahead, & work to keep advancing. #MedSky #IDSky 🧪 [1/2]
- #HepatitisB #reactivation in people living with #HIV when switched off #tenofovir... could become more of an issue as we move to dual #treatment and long-acting HIV regimens. #MedSky #IDSky #HIVSky #PLWH #HBV #NoHep 🧪 doi.org/10.1093/cid/... @cidjournal.bsky.social @cnwl.nhs.uk @uclh.bsky.social
- It's 💊World Antimicrobial Resistance Awareness Week💊. Great to see #HIV #hepatitis & #STI themes being unified to share expertise, resources & infrastructure through the launch of an integrated framework. A call for investment and action! 🧪 #WAAW #AMR #HBV @who.int www.who.int/publications...
- Project 'MoLo' for #Mongolians in #London offering education & screening focusing on #liver & #metabolic health & viral #hepatitis - fantastic community uptake. #MedSky #LiverSky #PublicHealth #Mongolia #NHS #NoHep #InclusionHealth #HBV @emilymartyn.bsky.social @crick.ac.uk @uclnews.bsky.social 🧪🇲🇳
- 📢 OPEN CALL for applications from early career group leaders… join this brilliant institute which provides a platform for #science without boundaries. All disciplines welcome incl clinician scientists 🧫🔭🔬🧬🧪🩺🩻🦠🌍 @crick.ac.uk www.crick.ac.uk/careers-stud... #career #PostDoc #STEM #research #funding
- No words wasted in this headline: "Bleeding to death: the #science & #technology growth emergency". #Visa hostility holds us all back. Far-reaching implications for economy, equity, excellence & ethics. 🧪 @houseoflords.parliament.uk #STEM #UK #research publications.parliament.uk/pa/ld5901/ld...
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- Reposted by Philippa MatthewsPAHO meets this week to decide if we’ve lost measles elimination status. I warned in this interview that we’re marching toward that threshold—and getting this close signals widening vaccination gaps and eroding public health capacity. 🔗 www.scientificamerican.com/article/meas... #Vaccines #Measles
- www.theguardian.com/society/2025... Yes this is happening in the NHS… and yes it’s also happening in schools, on buses, in cafes, at sports events and on the street. Nowhere is immune. Frightening times. #racism #UK #NHS
- End of #USAID part of the ebb and flow of misplaced global health interventions? No doubt the abrupt termination of programmes is a disaster, but what comes next, & can the global community work to support local solutions? #MedSky #Ebola #HIV #PublicHealth 🧪 www.theguardian.com/us-news/2025...
- Community engagement in #Kilifi #Kenya to understand experiences & barriers to care for people living with #hepatitis #HBV in #Africa. @lou-downs.bsky.social @wellcometrust.bsky.social @ndm.ox.ac.uk @kemriwellcome.bsky.social #MedSky #IDSky #stigma #NoHep 🧪 journals.plos.org/globalpublic...
- ‘Why #trains feel unsafe’. I agree… but should also note my commute feels unsafe *every day* with 10-15 people, plus luggage, bikes, dogs crammed into the link space between carriages. A disaster waiting to happen. I have raised concerns. Customer services don’t reply. #ChilternRail @theipaper.com
- #Cholera is spreading fast. As for so many infectious diseases, we do have the tools to intervene… but poverty, neglect, disasters, and lack of real political buy-in perpetuate an epidemic ecosystem. @who.int @drtedros.who.int #MedSky #IDSky #EpiSky 🧪 www.theguardian.com/global-devel...
- #Treatment of #hepatitisB infection: huge consortium effort via the Health Informatics Collaborative. 🧪 #NHS data to inform clinical care, public health practice, funding & policy. #MedSky #HBV #NoHep @nihr.bsky.social @ouhospitals.bsky.social hic.nihr.ac.uk/viral-hepati... doi.org/10.1111/jvh....
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- All opportunities to develop and share robust evidence to help us enhance progress towards #elimination of viral #hepatitis should be welcomed! Note special issue of #BMCInfectiousDiseases planned for 2026. #HepSky #MedSky #GastroSky #IDSky 🧪
- Even a one year pause in #PEPFAR funding predicted to cause >10,000 new #HIV infections over 5 years in #Africa. As always, vulnerable groups hit hardest… but impact for us all. @wellcometrust.bsky.social @who.int #LancetHIV #FundingCuts #MedSky #IDSky 🧪 www.sciencedirect.com/science/arti...
- What has happened to your site @figshare.com? Our collections used to be a lovely summary with thumbnails but all that nice formatting has vanished. Old / new views shown as screenshots. No response from help desk. Is anyone else having problems? #figshare #openaccess #publishing 🧪
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- Triple #elimination is possible - we have the tools to prevent vertical transmission of #HBV, #HIV & #syphilis. Congratulations to #Maldives on doing it, evidencing it & maintaining it... hoping more will follow your lead. 🇲🇻 🧪 #PaedSky #PedSky #MedSky #PMTCT #IDSky @who.int @sdgactioncampaign.org
- UK and international aid cuts are fuelling a worldwide health crisis: so how can we push back? Some questions and reflections here: www.bmj.com/content/390/... #GlobalHealth #MedSky #EpiSky #FundingCuts #NIH #NIHR @who.int @uclnews.bsky.social @crick.ac.uk 🧪
- UK and international aid cuts are fuelling a worldwide health crisis: so how can we push back? Some questions and reflections here: www.bmj.com/content/390/... #GlobalHealth #MedSky #EpiSky #FundingCuts #NIH #NIHR @who.int @uclnews.bsky.social @crick.ac.uk 🧪
- #PANDAS: An #inflammatory or #autoimmune syndrome that is poorly understood: we need urgent #research, clinical pathways, education & multidisiplinry collaboration. Who is leading? Where is the funding? #PANS #immunology #MedSky #PaedSky #PedSky 🧪 sunlightlater.substack.com/p/one-year-o...
- The problem is: unscrupulous people tick the boxes, fill in more forms, & get their work published, while decades of meticulously collected population data get thrown out by the publishers because those who stick to rules aren’t willing to scissor through the red tape (I know because I’m in there) 🧪
- Early career group leader positions are open @crick.ac.uk. Diverse #science being done across many fields, all under one roof but with global connections, from molecules to patients to policy. 🧪🔬🧬🦠🌍💊🩺💉⚛️⚗️
- We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...
- The impact of cutting #ClinicalTrials - yes this is certainly very bad for investigators & #patients… but also for #biotech, drug development, #academia, training & scientific progress, global collaboration, economic health, and so, in fact, all of our futures. 🧪 #MedSky @naturemedicine.bsky.social
- The number of people known to be living with #HBV is reported to have tripled in some areas of #SouthAfrica… as indeed in the #UK through routine screening of #NHS #EmergencyDepartment attendees. Increasing #diagnosis is essential to provide linkage to care & life-saving treatment. 🧪 #hepatitis
- This is interesting as we realise something similar for hepatitis #viruses… maybe we should talk less about ‘resistance’ (binary) and more about ‘susceptibility’ (shades of grey). #AMR #HBV #AntimicrobialResistance #Infection #IDSky 🧪
- Pleased to see this out today in @lancetmicrobe.bsky.social www.sciencedirect.com/science/arti.... We estimate the independent effects of AMR genes on MIC at a drug-bug level and challenge the idea that resistance is a binary phenomenon.
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