We also found that high fitness in populations evolved in the complex environment was driven by rare variants (frequency <0.1%) that inhibited the ancestral strain, which was used as a common competitor for fitness measurements.
Oct 16, 2023 20:08Ultimately, we hope this paper will inspire more work into how ecological interactions evolve during diversification.
In particular, the potential for the sort of synergistic interactions we observed to impact P. aeruginosa infections is ripe for further research!