Patients with a prothrombotic clinical course often associated with thrombocytopenia may have a monoclonal paraprotein, even at low levels, that activates platelets by binding to platelet factor 4. Read the Brief Report:
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VITT-like Monoclonal Gammopathy of Thrombotic Significance | NEJM
Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is associated with antibodies
that target platelet factor 4 (PF4) and are heparin-independent. VITT antibodies are
implicated in acute,...
