Nature research paper: Adenosine signalling drives antidepressant actions of ketamine and ECT
go.nature.com/3Ln1gh6
Adenosine signalling drives antidepressant actions of ketamine and ECT - Nature
Adenosine signalling is identified as the central mechanism of action of the antidepressant effects of ketamine and electroconvulsive therapy, and newly developed analogues of ketamine exhibit improved antidepressant efficacy with reduced side effects.
