Method of the Year 2025: This Comment from the Murthy lab showcases how complete connectomes can lead to hypotheses about circuit function and generate predictions that can then be tested with genetic tools, as illustrated with examples from the Drosophila community.
www.nature.com/articles/s41...
Linking structure and function: biological insights from fly connectomes - Nature Methods
Detailed maps, or connectomes, of the fly brain and nervous system reveal how circuit architecture (wiring) shapes both neural activity and behavior. These maps already demonstrate that it is possible...
