Microbial Pathogenicity Mechanisms
Research group @leibniz-hki.de in Jena, Germany.
Studying pathogenicity of yeast-y beasties in the 𝘊𝘢𝘯𝘥𝘪𝘥𝘢 clade. 🧫🔬🦠🍄
Head: Prof Bernhard Hube
Webpage: leibniz-hki.de/en/microbial-pathog…
- Check out our newest publication with @garymoran.bsky.social and Derek Sullivan in @microbiologysociety.org! Together, we investigated the individual roles of the TLO gene family members for Candida albicans' virulence. 🔬🧬🧫 👉 www.microbiologyresearch.org/content/jour... @leibniz-hki.de
- Don't miss Bernie's #MycoTalk!
- ✨️🎄 Wrapping up the year with our Christmas party! Thanks to @aps-hki.bsky.social and @sarsarela.bsky.social for celebrating with us! 🎁 Thanks to everyone who made 2025 such a great year of research and collaboration! Wishing you all happy holidays and a restful break! ✨️🫶 @leibniz-hki.de
- Reposted by Microbial Pathogenicity MechanismsFunded PhD position 3/9: Investigate how Candida albicans lipases shape fungal-bacterial interactions & benefit from the PhD training program ILRS 2.0. Apply by 13 Dec. 🎓 lmy.de/VyUor #PhDOpportunity #ScienceJobs #LeibnizHKI
- Reposted by Microbial Pathogenicity MechanismsFunded PhD position 4/9: Advance image quantification of organ-on-chip-based experiments within JIPipe & benefit from the PhD training program ILRS 2.0. Apply by 13 Dec. 🎓 lmy.de/tSJYf #PhDOpportunity #ScienceJobs #LeibnizHKI
- Reposted by Microbial Pathogenicity MechanismsMeet our #November feature Sophia Hitzler, a doctoral researcher at Leibniz-HKI, in this year’s #calendar 2025! From a fascination with fungi 🍄 to mentoring 👩🏫 and an unexpected dream job 🐳, discover her journey here: lmy.de/sBQAV #FacesOfScience #LeibnizHKI @aps-hki.bsky.social
- Reposted by Microbial Pathogenicity Mechanisms🎙️ For #WAAW, our Director Axel Brakhage joins the German podcast “Contagious Enthusiasm” to discuss natural products in antibiotic development, the need of innovative #AMR strategies & the challenging conditions for researchers. lmy.de/EWdVZ 🎧 Spotify: lmy.de/bsezx 🎧 Deezer: lmy.de/Jzccq
- Reposted by Microbial Pathogenicity MechanismsFunded PhD position 1/9: Explore RNA modification by natural products across species & benefit from the PhD training program ILRS 2.0. Apply by 13 Dec. 🎓 lmy.de/szeVW #PhDOpportunity #ScienceJobs #LeibnizHKI
- Reposted by Microbial Pathogenicity MechanismsFunded PhD position 2/9: Study neutrophil extracellular vesicles as a key defense mechanism against Aspergillus fumigatus & benefit from the PhD training program ILRS 2.0. Apply by 13 Dec. 🎓 lmy.de/yisip #PhDOpportunity #ScienceJobs #LeibnizHKI
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- Reposted by Microbial Pathogenicity Mechanisms📖 Perfect weekend reading for fungal fans! 😉 Our @mpm-hki.bsky.social colleagues uncover how #CandidaAlbicans manages to invade tissue as hyphae but spread as yeast. Published in @femsjournals.bsky.social. 🧑🏻🔬: @jlspragu.bsky.social
- #C.albicans invades tissues as hyphae but spreads as yeast, How? @jlspragu.bsky.social & coll. show yeast can reach the bloodstream by hitchhiking with invasive hyphae or by switching forms. 🧫 More clues for understanding systemic infections ! 👉 buff.ly/0vklJeb
- Reposted by Microbial Pathogenicity Mechanisms🎉 #LeibnizHKI has again been honored with the TOTAL E-QUALITY rating for our equal-opportunities personnel policy – for the 5th time in a row! This year, we also received the Sustainability Prize 2025 for our long-term commitment to equality, diversity & inclusion. 🗞️✨ lmy.de/zVSiL #TotalEquality
- Check out @jlspragu.bsky.social latest paper! @leibniz-hki.de
- #C.albicans invades tissues as hyphae but spreads as yeast, How? @jlspragu.bsky.social & coll. show yeast can reach the bloodstream by hitchhiking with invasive hyphae or by switching forms. 🧫 More clues for understanding systemic infections ! 👉 buff.ly/0vklJeb
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- Reposted by Microbial Pathogenicity Mechanisms🎉 We warmly congratulate Dr Alexander Mosig on his new professorship for Alternative Methods to Animal Testing in Infection & Inflammation Research at #JenaUniversityHospital! From Jan 2026, he’ll also join our Cluster to share expertise in #OrganOnChip and infection research.
- Reposted by Microbial Pathogenicity MechanismsA great turnout for our latest Microverse Seminar! 🍕🔬 @ameliabarberphd.bsky.social, Junior Group Leader #FungalInformatics, shared fascinating insights in her talk “From Ecology to Genomes: Unraveling Fungal Pathogenicity Across Scales.” Lively discussions and great connections followed!
- Reposted by Microbial Pathogenicity MechanismsWe proudly present: the 2025 Halloween Lab Pumpkin Carving Edition!!! 😁🥳👻
- Reposted by Microbial Pathogenicity Mechanisms🎥 New "3 Questions for …" episode! Prof. Miriam Rosenbaum shows how microbes can produce antibiotics, bioplastics, and find balance under stress. Discover how our #ClusterOfExcellence brings interdisciplinary science to life! 🌱🔬 www.youtube.com/watch?v=FA45...
- Reposted by Microbial Pathogenicity Mechanisms🍁 Meet our #October #calendar 2025 feature: Zoltán Cseresnyés, imaging specialist at our @appsysbio.bsky.social research group. From 1980s Hungary to super-resolution microscopy at Cambridge, he now helps researchers unlock insights from complex images. 🔬🌌 lmy.de/LsPim #FacesOfScience #LeibnizHKI
- Reposted by Microbial Pathogenicity Mechanisms📣 I’m excited to share two open positions in my lab @leibniz-hki.de. For this interdisciplinary project with @luziagyr.bsky.social, I’m seeking (1) an enthusiastic PhD student interested in fungal natural product research and genetic engineering, as well as (2) a technical assistant 👇🏻
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- “Pour some sugar on me” — environmental #CandidaAlbicans strains on a sugar diet can evolve enhanced virulence and antifungal resistance. Read our @leibniz-hki.de most recent discovery @plos.org doi.org/10.1371/jour... (1/2)
- It's a wrap! Thanks to the organizers at @microbiologysociety.org for this great #Candida2025 conference! 🍄👏😊 And congratulations to our PhD student Myrto who won a prize for her excellent poster presentation! 🥳🎉 @leibniz-hki.de
- Hope y'all enjoyed our talks at #Candida2025! Theresa presented yesterday one of her PhD projects about the C. glabrata-macrophage interaction. Tim presented today his work about the antibacterial mechanisms of candidalysin, and Sascha presented Osama's work on C. albicans' lipases. @leibniz-hki.de
- At today's poster session at #Candida2025 come and check out Anna's poster #B022! She presents her PhD project about Candida albicans protein kinases and how they affect pathogenicity. @microbiologysociety.org @trr124-funginet.bsky.social @leibniz-hki.de
- Don't miss our posters at #Candida2025 today! Myrto presents poster #A12 about dissecting C. albicans isolates using reporter cell lines. Steffi's poster #A6 is about ECE1 in non-albicans Candida species. And Verena presents her multi-reporter cells at poster #A24. @microbiologysociety.org
- The #Candida2025 meeting has started! And what a great kick-off with these two keynote speakers: @slg1717.bsky.social introduced her group's work around IL-17 and our boss Bernie presented a great overview about our group's candidalysin research. 🍄🧬🔬 @leibniz-hki.de @microbiologysociety.org
- On our way to the #Candida2025 hosted by the @microbiologysociety.org. Looking forward to see you there! 😊🍄
- Excieted to see @fungalmeg.bsky.social from #UNSW #Sydney present her groundbreaking work on harnessing the human microbiome to combat #CandidaAlbicans, along with advances in antifungal polymers we at @leibniz-hki.de have had the pleasure to collaborate on in the past!
- What a great talk by Megan Lenardon @fungalmeg.bsky.social from the #UNSWSydney! She visited our lab today @leibniz-hki.de and presented her group's work about how to antagonize #Candida albicans infections, either by novel antifungal polymers or via microbiome-based therapeutics. 🦠🧫🔬
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- Reposted by Microbial Pathogenicity MechanismsDose makes the difference! #Candidaalbicans uses the toxin #candidalysin not only to cause infections but also to quietly colonize the mouth – too little fails, too much triggers immune defense. @natmicrobiol.nature.com @mpm-hki.bsky.social picture credits: Erik Böhm, @leibniz-hki.de
- #CandidaAlbicans needs the toxin candidalysin to colonize the oral cavity in mice. A new sudy in collaboration with @lableibundgut.bsky.social and @pasteur.fr shows that candidalysin enables the fungus to cross the outer skin layer, resist the immune response, and maintain its niche—(1/2)
- 🚨New paper out in microLife! We uncover how Candida albicans yeast cells cross intestinal barriers during infection. 📖 Read more: academic.oup.com/microlife/ad...
- Paul Mathias Jansen presenting his exciting work comparing environmental and clinical #CandidaAlbicans strains at #DGHM @leibniz-hki.de
- Excellent talk! Our Postdoc Steffi Allert presented another part of Tim's @microverse.bsky.social -funded project about the role of ECE1 (the gene that encodes candidalysin) in non-albicans #Candida species. 🧬🍄 Feel free to find her during the coffee break for further questions! @leibniz-hki.de
- Hope y'all enjoyed Tim's talk at the #DGHM as much as we did! He presented his @microverse.bsky.social -funded PhD work on the antibacterial mechanisms of candidalysin. 🦠🍄🧫 He's still around for a chat in case you have questions about his project! 😊 @leibniz-hki.de
- Well done! Myrto's Master's student Taniya Banerjee presented her work at the #DGHM about infection dynamics of clinical #Candida albicans isolates.🍄😊 @leibniz-hki.de
- And another excellent talk at todays #EukaryoticPathogens session at the #DGHM by Myrto Katsipoulaki! 😊 She presented her #LPI -funded project about designing multi-reporter cell lines. 🎆🧬 If you have questions about her work, feel free to ask her during the coffee break! @leibniz-hki.de
- And another excellent talk at todays #EukaryoticPathogens session at the #DGHM by Myrto Katsipoulaki! 😊 She presented her #LPI -funded project about designing multi-reporter cell lines. 🎆🧬 If you have questions about her work, feel free to ask her during the coffee break! @leibniz-hki.de
- Hope y'all enjoyed Tim's talk at the #DGHM as much as we did! He presented his @microverse.bsky.social -funded PhD work on the antibacterial mechanisms of candidalysin. 🦠🍄🧫 He's still around for a chat in case you have questions about his project! 😊 @leibniz-hki.de
- Hope y'all enjoyed Tim's talk at the #DGHM as much as we did! He presented his @microverse.bsky.social -funded PhD work on the antibacterial mechanisms of candidalysin. 🦠🍄🧫 He's still around for a chat in case you have questions about his project! 😊 @leibniz-hki.de
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- Reposted by Microbial Pathogenicity Mechanisms🔎 Find us at the 77th #DGHM Meeting in #Jena! Gabriele Pradel, Anja Lührmann, Sandra Reuter, Bärbel Stecher and others are happy to tell you more about our German network for women in infection research! 💜 👩🔬@gabrielepradel.bsky.social @sandrareuter.bsky.social @baerboletta.bsky.social
- Reposted by Microbial Pathogenicity MechanismsBiophelion, a @leibniz-hki.de spin-off, turns industrial waste into sustainable materials! 🌱♻️ Using a black yeast, they create biodegradable polyesters, pullulan & new eco-friendly surfactants. @sprind-de.bsky.social @tilltiso.bsky.social Pictures: @sprind-de.bsky.social, Tillmann Franzen
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- Excellent talks in this Plenary Session 3 at the #DGHM chaired by our #Postdoc Sascha Brunke! 👏😊 Don't miss out todays #EukaryoticPathogens Session in the afternoon with talks from our PhD candidates! @leibniz-hki.de
- And don't forget to join Mathias Jansen's talk on Wednesday! 🍄 He'll present his work as a PhD candidate in the last #EukaryoticPathogen session in the afternoon. 😊
- #DGHM2025 started already! Don't miss the talk by our PhD student Anna Möslinger in the #EukaryoticPathogens Session today!
- Tomorrow you can listen to an entire session with our talks! 😊 Our Master's student Taniya Banerjee, our PhD candidates Tim Schille and Myrto Katsipoulaki, and our PostDoc Steffi Allert will present their work - so don't miss the #EukaryoticPathogens session tomorrow! 🍄🧫🔬 @leibniz-hki.de
- #DGHM2025 started already! Don't miss the talk by our PhD student Anna Möslinger in the #EukaryoticPathogens Session today!
- #DGHM2025 started already! Don't miss the talk by our PhD student Anna Möslinger in the #EukaryoticPathogens Session today!
- Reposted by Microbial Pathogenicity Mechanisms🌍 Today is the #InternationalMicroorganismsDay! On this occasion, we are naming the Microverse #MicrobeoftheYear 2025: Candida albicans. Carried by up to 95% of people, it usually lives harmlessly in our bodies – but can also cause infections. www.microverse-cluster.de/en/news/micr...
- Reposted by Microbial Pathogenicity MechanismsAt this week’s #JEMS, Michael Zimmermann (@zimmermannlab.bsky.social & @embl.org) shared insights on how gut microbiota shape #drugmetabolism and carcinogen toxicity. Fascinating findings on cancer risk, #drugresponse variability, and limits of current models. Thanks for the inspiring talk!
- Reposted by Microbial Pathogenicity MechanismsVirusinfektionen sind ja leider oft nur die halbe Miete. Pilze finden geschwächte Körper nämlich auch ganz gut ⬇️ #zombies @leibniz-hki.de
- Reposted by Microbial Pathogenicity MechanismsJust a few more days to apply! ⏰
- My group at is hiring a PhD student to explore how fungal pathogens that live in the environment will adapt their genomes, acquire new phenotypes, and perhaps even increased infectivity as a result of climate change. Please share! More info and applications at @ jobs.uni-jena.de/vrbup
- Reposted by Microbial Pathogenicity MechanismsThe project, supported by the Free State of Thuringia, was co-financed by funds from the European Union as part of the European Regional Development Fund (ERDF). #ERDF #EU #Aufbaubank #DFG
- Reposted by Microbial Pathogenicity MechanismsA little more than 2 weeks to apply for a Postdoc position in our lab @leibniz-hki.de 👇🏻
- 📣 I’m recruiting a #Postdoc to help us further our understanding on the infection strategies of our human fungal pathogen. If you’re enthusiastic about research, our interdisciplinary group @leibniz-hki.de will be a good fit for you! Please share! jobs.hki-jena.de/jobs/Postdoc...
- Reposted by Microbial Pathogenicity MechanismsScience must be part of the climate solution. 🌱🌎 At #LeibnizHKI, we rethink workflows to reduce waste & save energy. Patrick Penndorf (@patricks-science.bsky.social) helps us with this. ➡️ www.leibniz-hki.de/en/press-rel... #Sustainability
- Reposted by Microbial Pathogenicity MechanismsSolar panels, recycling waste heat, efficient freezers. Small steps, big impact: We are working on making research and our institute more energy-efficient. #Sustainability #EnergyEfficiency #SolarPanels #LeibnizHKI
- Reposted by Microbial Pathogenicity MechanismsWe’re hiring a Postdoc in Gut Microbiome Metabolomics! Help us decode microbial metabolism and its impact on human health @leibniz-hki.de , Jena 🇩🇪 🔗 jobs.hki-jena.de/jobs/Postdoc...
- Reposted by Microbial Pathogenicity MechanismsWe’re hiring a Postdoc on Gut Microbiome–Host Interactions @leibniz-hki.de, Jena 🇩🇪 You'll create organ-on-chip models to study how microbes mediate host responses to xenobiotics jobs.hki-jena.de/jobs/Postdoc...
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- Reposted by Microbial Pathogenicity MechanismsSpotlight on our Leibniz Competition project “FuRTHER” on #WorldRNADay: Exploring how fungal ncRNAs may reprogram human gene expression. A new concept in infection biology by @mgblango.bsky.social, funded by the @leibniz-gemeinschaft.de. #InterkingdomCommunication #LeibnizHKI ➡️ lmy.de/bNyTX
- Reposted by Microbial Pathogenicity MechanismsMy group at is hiring a PhD student to explore how fungal pathogens that live in the environment will adapt their genomes, acquire new phenotypes, and perhaps even increased infectivity as a result of climate change. Please share! More info and applications at @ jobs.uni-jena.de/vrbup
- Reposted by Microbial Pathogenicity MechanismsNew PhD position @uni-jena.de and at our #ClusterOfExcellence! Join @ameliabarberphd.bsky.social's group to study #ClimateChange & #FungalPathogens. Interdisciplinary training, vibrant research network & great working conditions. Apply by Aug 31: jobs.uni-jena.de/jobposting/a... @uni-jena.de
- Reposted by Microbial Pathogenicity MechanismsYesterday, Thuringian Science Minister Christian Tischner visited #LeibnizHKI to learn about our junior research groups fighting the antibiotic crisis with high-tech. It was a pleasure having him with us! lmy.de/AYoYM @slavi-jan.bsky.social @jethrohemmann.bsky.social @luziagyr.bsky.social
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- Reposted by Microbial Pathogenicity MechanismsMaking a research institute more sustainable in just 2 weeks? The Leibniz-HKI and I took on the challenge... 🧵👇 The goal wasn’t just clean energy, but also less plastic in experiments, reducing chemical waste, and improving health & safety. #STEM #Greenlab @leibniz-hki.de
- Reposted by Microbial Pathogenicity Mechanisms📣 I’m recruiting a #Postdoc to help us further our understanding on the infection strategies of our human fungal pathogen. If you’re enthusiastic about research, our interdisciplinary group @leibniz-hki.de will be a good fit for you! Please share! jobs.hki-jena.de/jobs/Postdoc...
- Check out the newest publication by @aps-hki.bsky.social in @natcomms.nature.com! Sophia Hitzler, in collaboration with our alumnus #PhD Sophie Austermeier and current PhD student Anna Moeslinger, investigated how albumin affects Candida albicans' pathogenicity.
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- Reposted by Microbial Pathogenicity Mechanisms#MDRWISSEN feature explores how our researchers at @leibniz-hki.de are reviving #AncientDNA 🧬of microbes from Neanderthal teeth to discover new compounds, possibly even new #antibiotics! Read and listen the german article 👉 lmy.de/rMRxk @microverse.bsky.social @uni-jena.de #WernerSiemensStiftung
- Yesterday, Judith Behnsen from the University of Illinois & Chicago visited our lab @leibniz-hki.de and gave an amazing talk in the @microverse.bsky.social seminar. She presented her group's work about Salmonella exploiting Candida albicans' presence in the gut.🦠🍄 👉Her paper: doi.org/10.1101/2024...
- Reposted by Microbial Pathogenicity MechanismsJust out: Check out the interview of ACS infectious diseases with our PhD student Karen Cheng working on new inflammatory axis in vaginal candidiasis axial.acs.org/medicinal-ch...
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- What an afternoon! ✨️ Yesterday, we had our annual group excursion together with @aps-hki.bsky.social. We visited the Petersberg citadel in Erfurt🏰, participated in a chocolate workshop and prepared our own pralines🍫, and had a nice dinner together! 🍻🌃 @leibniz-hki.de
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