Xingru Chen et al. describe the role of the PhyK orphan kinease in Brucella obis. PhyK is a key regulator of cell envelope properties that can modulate host immune interactions.
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onlinelibrary.wiley.com/doi/10.1111/...
An HWE‐Family Histidine Kinase Modulates Brucella Cell Envelope Properties and Host Innate Immune Response
The HWE-family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of p...