Heather Brown-Harding
Imaging Scientist at Harvard Center for Biological Imaging. I help people do cool science. Lover of all
things microscopy & microbiology 🔬🦠
- 😬 At least the aqua stop did its job. (Water came out of tube when I adjusted it)
- Reposted by Heather Brown-HardingEp 24 - Understanding your thresholding options is the diff between a win and a loss in SO MANY workflows - gain that intuition, and SO MUCH is easier. The 1st of 3 episodes discussing why - inspired by OUR FIRST REAL READER QUESTION. @erinweisbart.bsky.social and I are actual advice columnists now!
- Ep 23 - So what actually IS CellPainting anyway? You may have heard of it if you're say, a fan of the @drannecarpenter.bsky.social - @shantanu-singh.cc lab (and who isn't????), but what, you know, is it? Let @erinweisbart.bsky.social break it down for you! youtu.be/9-d6DoHtgUY
- Reposted by Heather Brown-HardingIt’s 2026. There is a measles outbreak in the prison for babies
- Reposted by Heather Brown-Harding📣 Applications are open for work experience 🧪🔬 Aimed at local Y12 students from underrepresented backgrounds interested in science 🗓️ 27/07 – 31/07 Eligibility and selection criteria apply Applications by 01/03 More info: mrclmb.ac.uk/careers-and-... #STEM #WorkExperience #BiologyCareers
- Starting next week, our Cryo-EM is officially open!
- Got a non-sterile sample box from ibidi as part of their core sample program, so I obviously had to touch everything. The chamber slide is so squishy!
- Joystick keeps sticking. Anyone have suggestions on how to clean this other than moving it in all directions with a cotton swab shoved in?
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- Reposted by Heather Brown-HardingWe have two funded postdoctoral positions available. Topics encompass: -Next gen light-sheet fluorescence microscopy instrumentation -Structured illumination microscopy and other approaches to extend the resolution limit. -Nonlinear microscopy combined with adaptive optics / phase conjugation
- I swear, only in my core do you walk into the conference room with a 18" cucumber and after the first question of what's up with your whole cucumber, you get asked can I have some of it try to clear it...
- Anyone know anything about Capital Equipment Network? At least one of our systems is listed and we have no connection to them for booking or "requesting a quote." capneteq.com/equipment/JF...
- I took morning childcare and my husband is doing afternoon childcare. This is what he is doing in our yard. Why do real snowdays not exist anymore? Stupid zoom...
- Ok, one more dog in snow post and then back to the regular posts. This is my dog bouncing through the snow to get to the less deep area under the snow. She's 10 and had cancer, so not as graceful as she once was 😂
- My dog, Ginger Snap, enjoyed the storm for about 10 minutes, then wanted to curl up on the couch with the blanket my mother-in-law knitted just for her.
- Come on Harvard! Even Market Basket is closing!
- Harvard: We are emailing you that there will be 15-20" of snow by tomorrow morning. We will NOT be closing. Me: 👎
- Reposted by Heather Brown-HardingThe next deadline for @jcellsci.bsky.social FocalPlane Training Grants is 20 February. These grants are open to early-career researchers in cell biology that require funding to attend a microscopy or bioimage analysis training course. www.biologists.com/grants/jcs-f...
- Reposted by Heather Brown-Harding🚨 Job Alert! 🚨 We have an opening at our Microscopy Core Facility in Turku 🇫🇮. If you love imaging 🔬 and helping scientists succeed, we want you! 👇 abo.rekrytointi.com/paikat/index... #Microscopy #ScienceJobs #CoreFacility #Imaging @turkubioscience.bsky.social
- Oh look, people don't like AI marketing to them... www.sciencedirect.com/science/arti...
- The BINA Communication group has a new initiative this year! We are forming a multilingual subgroup to translate important documents into Spanish and French. You can participate as much or as little as you would like. docs.google.com/forms/d/e/1F...
- Reposted by Heather Brown-Harding🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs). Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬 Details in thread 🧵👇 #ScienceSky #Postdoc #AcademicJobs Please RT🫶
- Reposted by Heather Brown-HardingEp 23 - So what actually IS CellPainting anyway? You may have heard of it if you're say, a fan of the @drannecarpenter.bsky.social - @shantanu-singh.cc lab (and who isn't????), but what, you know, is it? Let @erinweisbart.bsky.social break it down for you! youtu.be/9-d6DoHtgUY
- Ep 22 - while we all love CellProfiler (right??), we know that often the challenging part is handling the "bookkeeping" to get your data into it in the first place. @erinweisbart.bsky.social and I do a quick overview, and then point to great longer-form materials. Welcome to AE/DB 2026!
- Coolest new feature from the Yokogawa HCA: changing color if the plate isn't on the loader correctly. Removes a lot of anxiety. 💯
- In Greater Boston? Come to our Cryo-EM Grand Opening!
- But women are "too emotional" to be leaders 🙃
- Trump yells “fuck you” and flips off an auto worker in Michigan who yelled “pedophile protector” www.tmz.com/2026/01/13/t...
- Today's lowest stake dilemma: I had a coffee, there will be a talk with coffee at 10:30. Do I have a cup of tea in the meantime? 😄
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- I'm reading about the terrible storm in the UK on the BBC, so I WhatsApp my friend to see how she is. This is the Peak District 😂
- I get to help image a starfish today and I'm stoked! I love unusual samples
- We are hiring a specialist for Cryo-EM that will be shared between Harvard FAS and HMS. Check it out! academicpositions.harvard.edu/postings/15677
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- The dimensions on my crochet snake are giving "sperm" 😂
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- Since they don't expect anyone to be working today, they have made our hallway look like a scene out of Dexter...
- Reposted by Heather Brown-Harding✨ Blinking #nanobodies that work for single-molecule localization 🔬 Our new preprint shows that the self-blinking dye JF635b restores robust, buffer-free blinking in #nanobodies, enabling reliable #dSTORM, #MINFLUX, and more, without chemical-switching buffers. Opening new possibilities for #ExM!
- Finally a year that week before Christmas, I only have one training. And it's someone that has used the 880 weekly for the last year and wants to use the 980 over break when he doesn't have to compete with anyone to use it
- Trying not to screw over 2026 Heather, but 2025 Heather wants to do the bare minimum until break 😂
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- Reposted by Heather Brown-HardingEveryone else go home — this is the year we secure ABOLISH ICE on a Chicago Snowplow chicagoshovels.org
- Reposted by Heather Brown-Hardingwho has favorite ways to measure hypoxia in tissues using immunofluorescence/microscopy? i guess maybe the gold standard is pimonidazole/hypoxyprobe- is there any reliable way that doesn't involve injecting anything in vivo? (like what do people do for human tissues?)
- Well, it's official, you can catch me at #ABRF2026 where I will be presenting on Facility Marketing at the Monday "mini-workshop."
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- Help me come up with a story to tell today's users that's cooler than I fell on black ice 😝
- I highly suggest putting random things on the microscope. I think I just took an image for the Nikon Small World image contest... if invertebrate sex doesn't disqualify it 😆 And no, I didn't realize it until after I finished an hour-long acquisition
- Check out our poster #ASCB2025
- It is 9F/-13C out, so time for dino santas knit sweater.
- Reposted by Heather Brown-HardingWe mapped the whole human fallopian tube in 3D and at single-cell resolution via our CODA workflow. More about this work here: biorxiv.org/content/10.1...
- Reposted by Heather Brown-HardingLooking for another 25-35 responses from PCOS patients to give this student at least 50 to analyze in their honors research. We've had no luck with physician/provider responses, it may be too tough out there in 2025, but the patient responses are interesting. #MedSky
- Rafiki voice: It is time! [to begin wearing obnoxious sweaters]
- Reposted by Heather Brown-HardingInterested in Zebrafish brain imaging? We released a 3D printed mold that's is super helpful for us. Check it out Customizable FDM-based zebrafish embryo mold for live imaging www.biorxiv.org/content/10.1... Work by Marcela and Jaakko in the lab
- Reposted by Heather Brown-HardingA specialized appendage responds to female sex hormones, allowing male octopuses to find their sex organs in the dark. scim.ag/4roFry3
- I might finish my Power App in the next few weeks, so HCBI users can report problems. It sends an email to our joint email, and then they can check the status of any problems without getting constant emails. Wish me luck! (Because every time I fix one thing, a new thing breaks 😆)
- I had a new coworker who had worked with us for 2 weeks. We were at a holiday party, and they asked, "Do they have anything other than beer and wine?" My response was, "they don't do liquor at work parties." She stared at me until I realized the question. "Oh, soda and seltzer." 😬
- Reposted by Heather Brown-HardingA holiday demonstration of the different penetration depths of red and blue light into tissue. #optics
- It's a bit squished from being on a slide for yesterday's confocal images, but I hope you enjoy my uncleared tick imaged on the Zeiss Lightsheet 7, with multiview fusion.
- Good.
- Reposted by Heather Brown-HardingCheck out our latest issue where we interview Cassandra Extavour, who studies the evolution of the genetic mechanisms employed during early animal embryogenesis to specify cell fate, development, and differentiation at Harvard University. www.cell.com/current-biol...
