MGH Medical Practice Evaluation Center (MPEC)
MPEC is dedicated to improving clinical outcomes, increasing value in health policy, and informing public health through research and training
mpec.massgeneral.org
- A new study by @mgh-mpec.bsky.social investigators in BMC Public Health found that HIV medication price accounts for 74% of projected HIV-related costs for youth with HIV
- Consistent ART use is needed for improved health outcomes and affordable ART is critical. pubmed.ncbi.nlm.nih.gov/41351116/ @anneneilan.bsky.social @andreaciaranello.bsky.social @mgh-mpec.bsky.social @emilyhylemd.bsky.social @clareflanaganmph.bsky.social
- MGH investigators analyzed data from sexual health clinic sites in the Boston area and found that among those with #PrEP indications, young females were less likely to be prescribed PrEP compared with male peers and older females @anneneilan.bsky.social
- Led by researchers at @mgh-mpec.bsky.social and Zimbabwe-based collaborators, modeling analysis in @jidjournal.bsky.social projects that long-acting injectable ART could prevent infant infections, improve maternal life expectancy and be cost-effective in Zimbabwe. #HIV #maternalandchildhealth
- Dr. Ingrid Bassett was one of the recipients of the @impactatharvard.bsky.social's Paid Service Leaves. She will be working with @massdph.bsky.social to design & evaluate childhood vaccination outreach and communication strategies. Read more at: www.hks.harvard.edu/announcement...
- Congratulations to Dr. Crystal North on being awarded a CHEST/ALA grant to study community air pollution exposure and COPD.
- Just out in NEJM: Drs. Siedner, Gaziano, Magula & colleagues show substantially improved hypertension care in rural South Africa by transferring treatment from clinic to home w/BP machines for self-monitoring, CHW check-ins, and remote care by nurses with an mHealth app.
- A new study in @annalsofim.bsky.social found that participants with social risk factors at the time of SARS-CoV-2 infection had greater risk for subsequent long COVID than those without. Read more here: www.acpjournals.org/doi/10.7326/...
- Hyle et al. found that the WHO-recommended package for advanced HIV disease (AHD) would improve clinical outcomes and quality-adjusted life expectancy and be cost-effective in Malawi and is likely to be cost-effective in most high burden HIV settings. Read here: www.thelancet.com/pdfs/journal...
- Dugdale et al. found that maternal HIV viral load was strongly correlated with infant transmission risk. These data support #U=U in pregnancy/birth.
- Congratulations to MPEC Investigator Aima Ahonkhai on receiving the HMS Diversity Inclusion and Community Partnership Faculty Fellow Award. This will support her work on Cutting Out Stigma, which uses barbershop-based interventions to combat HIV stigma among Black men in the Southern U.S.
- Adolescent girls & young women are disproportionately impacted by HIV in South Africa. MPEC investigators & Desmond Tutu Health Foundation & @yalesph.bsky.social collabs show long-acting cabotegravir for HIV #PrEP for AGYW could reduce infections & transmissions and could be cost-saving at $65/year.
- STI testing in hair salons in South Africa reaches women with risk factors for STIs and HIV, appears acceptable and feasible, and reveals a high STI prevalence @mgh-id.bsky.social journals.lww.com/jaids/abstra...
- In a new modeling study, MPEC researchers found that anti-HIV broadly neutralizing antibodies (bNAbs) could prevent up to 42% of new pediatric HIV infections and be cost-effective for all infants born in high (>15%) HIV prevalence settings akin to a vaccine
- Dr. Suzanne McCluskey and colleagues are speaking on a panel today at #CROI2025. Join at 4pm PST to hear about their work on integrase failure and resistance! @mgh-id.bsky.social
- On the final day of #CROI2025 , see more MPEC research at the 2:30pm PST poster session @emilyhylemd.bsky.social @ankurfactorial.bsky.social @mgh-id.bsky.social
- Dr. Mark Siedner presenting on coronary atherosclerosis among PWH in Uganda today at #CROI2025 ! Join the Cardiometabolic Complications & Aging session to listen!
- Come hear MPEC investigators share their research at #CROI2025 ! We have several posters during today’s session at 2:30pm PST. @caitlindugdale.bsky.social @anneneilan.bsky.social @andreaciaranello.bsky.social @iddocjen.bsky.social @mgh-id.bsky.social
- MPEC faculty @anneneilan.bsky.social and long-time collaborator Dr. Linda-Gail Bekker contextualize recent research on the impact of abrupt #PEPFAR cuts in @statnews.com www.statnews.com/2025/03/01/p...
- Dr. Ingrid Bassett and teams at @ahri-news.bsky.social and @mgh-mpec.bsky.social assessed uptake of PrEP and contraception among women receiving an innovative package of care in hair salons in Durban, South Africa. doi.org/10.1186/s128... #HarvardCFAR
- MPEC researchers & collaborators project the impact of abrupt #PEPFAR cuts in South Africa, estimating years of life lost and detrimental epidemiological impacts. @anneneilan.bsky.social @andreaciaranello.bsky.social @mgh-id.bsky.social www.acpjournals.org/doi/10.7326/...
- Dr. Crystal North was awarded the 2025 Young Physician-Scientist Award by the American Society for Clinical Investigation for making notable achievements early in her research career! Congratulations Dr. North! @the-asci.bsky.social
- Congratulations to Dr. Lisa Bebell on being promoted to Associate Professor of Medicine at Harvard Medical School!
