Matt Coelho
Cancer Research UK Career Development Fellow at the Wellcome Sanger Institute - gene editing - drug resistance - cancer
- Fully funded postdoc position in my team. CRUK and Wellcome Sanger Institute. Want to work on lung cancer + functional genomics? Only 1 more week to apply!💥
- new year, new job?! Exciting postdoc position opening in my lab at the Wellcome Sanger Institute. Fully funded by CRUK sanger.wd103.myworkdayjobs.com/en-US/Wellco... find out more at www.coelho-lab.com
- Our paper on genetic mediators of cancer cell susceptibility to T cell killing is out today online: www.cell.com/cell-reports... These genes could serve as biomarkers of sensitivity to immunotherapy - they modulate IFN-g and TNF-a response and are lost in some tumours Thread below on our preprint👇
- Excited to announce our preprint today @biorxivpreprint.bsky.social Using functional genomics, we map the genetic determinants cancer cell sensitivity to tumour-reactive T cells: www.biorxiv.org/content/10.1...
- Reposted by Matt CoelhoNew biomarkers for cancer immunotherapy have been identified. 🔎 Researchers found that loss of two genes, CHD1 and MAP3K7, makes tumours more likely to respond to immunotherapy. The findings could help support more personalised cancer treatment 👇 bit.ly/4sMBTq2
- new year, new job?! Exciting postdoc position opening in my lab at the Wellcome Sanger Institute. Fully funded by CRUK sanger.wd103.myworkdayjobs.com/en-US/Wellco... find out more at www.coelho-lab.com
- Reposted by Matt CoelhoLooking to start your lab in generative biology / AI? Come join us at the @sangerinstitute.bsky.social Sanger is core-funded so you can generate data at scale to train the next generation of models and understanding. Design/Engineering/Chemistry/Proteins/Pathways! pls RT tinyurl.com/GenGenFaculty
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- Very neat idea to increase precision of base editors by modifying guide design, plus directed evolution!
- Engineered base editors with reduced bystander editing through directed evolution - @geochurch.bsky.social @harvardmed.bsky.social @wyssinstitute.bsky.social go.nature.com/4qmupbv
- A pleasure to talk about our research today with the amazing volunteers at St John’s ambulance in aid of @cancerresearchuk.org
- Reposted by Matt CoelhoApply for Multiplex Assays of Variant Effects training by 18 August! ⏰ Join our experts to learn how to strengthen your genetic disease research or clinical work using MAVE data. 🧬 Financial assistance available💸 📎Find out more: bit.ly/3EW3lh4 #MAVE25 #VariantInterpretation
- Reposted by Matt CoelhoComing up in September! ➡️Christina Kajba @ckajba.bsky.social & Michael Herger @michaelherger.bsky.social — pooled prime editing screens in haploid human cells ➡️Jon Acosta — multiplexed in vivo base editing screens #GeneticVariants #PrimeEditing ℹ️https://www.varianteffect.org/seminar-series/
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- Looking to combine ML and functional genomics to tackle cancer drug resistance? Exciting job opening at the Sanger! sanger.wd103.myworkdayjobs.com/en-US/Wellco...
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- Reposted by Matt CoelhoCome and join us! We’re hiring a new Group Leader in Generative Biology at the @sangerinstitute.bsky.social Building AI models or the data to train them? Core funding of >$130M a year for a faculty of ~30. www.nature.com/naturecareer... acrobat.adobe.com/id/urn:aaid:... pls RT!
- Excited to announce our preprint today @biorxivpreprint.bsky.social Using functional genomics, we map the genetic determinants cancer cell sensitivity to tumour-reactive T cells: www.biorxiv.org/content/10.1...
- less than one week remaining to apply 👇
- Excited to announce that we're recruiting a Staff scientist at the Sanger Institute to investigate drug resistance mechanisms in cancer using gene editing. Interested? Apply here: sanger.wd103.myworkdayjobs.com/en-US/Wellco...
- Reposted by Matt CoelhoNew Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. www.grc.org/synthetic-le.... Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
- Excited to announce that we're recruiting a Staff scientist at the Sanger Institute to investigate drug resistance mechanisms in cancer using gene editing. Interested? Apply here: sanger.wd103.myworkdayjobs.com/en-US/Wellco...
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- Today in BJC Reports, we summarise the outcomes from a multidisciplinary workshop focused on addressing cancer drug resistance. www.nature.com/articles/s44...
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- Reposted by Matt Coelholast couple days to apply (for free! from anywhere in the world!) to the Sanger 2025 PhD Programme — Deadline: 28th November 2024 (09:00 GMT) For more info, visit www.sanger.ac.uk/about/study/...
