- #HARMONi-6 & #OptiTROP-Lung04 both large phase-3 RCT in a china🇨🇳 only population. Both given Presidentials #ESMO25 Discussants commented re confirmatory trials in worldwide setting Is this necessary in 2025? Why don’t we consistently raise this question to EU/US trials?🇪🇺🇺🇸 #oncology #LCSM #oncskyOct 19, 2025 16:59