Louise Fets
Researcher with an interest in pharmacology and cancer metabolism, Group Leader @mrc-lms.bsky.social & CRUK Career Establishment Awardee
- Reposted by Louise Fets📣 We’re hiring 6 new Team Science postdocs! Our Team Science approach brings together interdisciplinary researchers to tackle questions no single field can solve alone. Find out more and download our brochure below
- Congratulations Will Scott and team @mrc-lms.bsky.social on some fantastic work looking at how adipose tissue remodels in obesity and weight loss.
- Seconded! Worth a look for anyone who wants to open a lab working on metabolic physiology and/or disease, or immunometabolism
- We're recruiting junior team leaders @mrc-lms.bsky.social This time we're looking for those working in human metabolic disease. It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us! lms.mrc.ac.uk/work/vacanci...
- Reposted by Louise FetsPaper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social
- Reposted by Louise FetsCongrats to the drug transport and tumour metabolism group, headed by @louisefets.bsky.social for winning two awards!
- #JobAlert! We have an opening for a postdoctoral scientist in #CancerMetabolism in my lab @mrc-lms.bsky.social. If you're interested in the role of metabolism in drug response and resistance in cancer, and would like to work in a fun and friendly team, check it out: lms.mrc.ac.uk/work/vacanci...
- We’re excited to share a new pre-print from the lab! Led by Carmen Ramirez Moncayo and a fantastic collaboration with several groups from across @mrc-lms.bsky.social & @imperialcollegeldn.bsky.social. Interested in #OvarianCancer, #PARPinhibitors or #DrugDistribution? please read on! bit.ly/45lpekS
- We asked whether intra-tumour heterogeneity affects drug distribution, and if this impacts drug response. To answer this, Carmen set up a multimodal imaging pipeline using PARP inhibitor-dosed patient derived explants (PDEs) from HGSOC tumours (big thanks to Paula Cunnea&Christina Fotopoulou!)
- Dosing ex-vivo, we could image drug distribution independently of tumour vasculature, to explore cell-intrinsic differences in drug accumulation. Mass Spec Imaging, with expert tutelage of @zoehall-icl.bsky.social, revealed particularly striking heterogeneity in rucaparib and niraparib-treated PDEs
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View full threadHeterogeneity is rife in all tumours and we’re excited to explore drug distribution with other drug/cancer combinations, and the implications for efficacy and resistance. Finally, a huge thank you to the Fets Lab members, all collaborators and of course the patients. We’d love to hear any feedback!
- Eeekkk HUGE congratulations @aakritijain.bsky.social and @robzonculab.bsky.social! 🎉 🎉 🎉 Such a cool story and very pleased to see it out!
- SO excited to share that a major part of the postdoctoral work in @robzonculab.bsky.social lab is now published: “Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins” www.science.org/doi/10.1126/...
- Reposted by Louise Fets🚨 Less than one week until the abstract deadline for the Mechanisms of Membrane Transport GRS!! 🚨 📅 Apply by Feb 16th! If you enjoy learning about novel insights into membrane transporters in beautiful places, this is the conference for you! 🧪 #STEMseminar
- Do you have new & exciting results to share about transport proteins and channels? 🧪 🤩 Come & join experts & early-career researchers for cutting-edge discussions in lovely Switzerland! 🏔️ Apply now for the 2025 Mechanisms of Membrane Transport GRS! ⬇️ www.grc.org/mechanisms-o... #STEMseminar
- Fantastic time at the lab's first retreat with @Alexis_Barr lab - great to get away and have some time for team building and big picture thinking. Very proud of how open and engaged both teams were. Until next time!
- Just back from a wonderful inaugural joint BarrXFets lab retreat with the wonderful @louisefets.bsky.social team. Super proud of both teams for their efforts over the two days - both scientifically & on karaoke
- Really excited to be invited to this GRS event, these small group conferences are always a lot of fun and so great for learning and networking. Well worth a look for any ECRs in the membrane transport field!
- Do you have new & exciting results to share about transport proteins and channels? 🧪 🤩 Come & join experts & early-career researchers for cutting-edge discussions in lovely Switzerland! 🏔️ Apply now for the 2025 Mechanisms of Membrane Transport GRS! ⬇️ www.grc.org/mechanisms-o... #STEMseminar
- Exciting data on the pro-survival role of p21 in NSCLC! Congratulations Steve and @alexisbarr.bsky.social, and I hope this will be the first of many collaborative papers together! 🥰
- New Year, new paper! (Ok, it actually came out just before Christmas but who was working then?!) Here we show that p21 promotes the survival of non-small cell lung cancer cells, under normal growth & after chemotherapy: rdcu.be/d4kvU
- Huge congratulations @ginevradoglioni.bsky.social and @fendtlab.bsky.social! 🌟 Excited to read!
- Beyond excited to share that the main work of my PhD on how aspartate signaling drives metastasis is finally out in @nature.com ✨ -> go.nature.com/4gCYtuL A huge thank to the @fendtlab.bsky.social and all our collaborators for the terrific team work 🙏 A brief 🧵
- Reposted by Louise FetsExcited to announce two DFG-funded PhD positions to study Lipid Droplet Heterogeneity in cancer as part of FOR5815. Join us @dkfz-heidelberg if you are interested in #cancermetabolism and #lipidbiology jobs.dkfz.de/en/jobs/1673... jobs.dkfz.de/de/jobs/1673...
- Reposted by Louise FetsA PhD position in computational genomics is open in our group at Imperial/MRC LMS! 🌟 Join the DANIO-ReCODE Doctoral Network and work on gene regulation, evolution, development, and tissue regeneration. Open to all (except those residing in the UK in the past year). Deadline: 8 Jan 2025. t.ly/fDdDW
- New PI positions @mrc-lms.bsky.social 👀 It's truly a great place to start a lab, definitely worth a look if you're on the job market. Please share with your networks!
- We’re delighted to share our recruitment brochure for our current Programme Leader Track vacancies at the MRC Laboratory of Medical Sciences. You can download the brochure on our vacancy web page 👇 lms.mrc.ac.uk/work/vacanci...
- Reposted by Louise FetsWe are hiring! Programme Leader Track positions @mrc-lms.bsky.social up for grabs by up-and-coming researchers with a great start to their career who now aim to establish their own group in a translational discovery science institute of world leading excellence. lms.mrc.ac.uk/work/vacanci...
- We’re delighted to share our recruitment brochure for our current Programme Leader Track vacancies at the MRC Laboratory of Medical Sciences. You can download the brochure on our vacancy web page 👇 lms.mrc.ac.uk/work/vacanci...
- It's been a good year for the lab, with highs including a new PhD, paper submitted and an AACR grant won. Some bitter sweet moments saying goodbye to some lovely lab members, but welcoming some great new/returning ones too. Merry Christmas to you all from all of us ♥️🎄🥂 🌟
- Reposted by Louise FetsMedical research has transformed the treatment of #ovariancancer recently but resistance to the new class of drugs - parp inhibitors - must be overcome in order to realise their full potential. Congratulations Dr @louisefets.bsky.social & Dr Moncayo - the patient community is cheering you on!
- 🎉 Congratulations @louisefets.bsky.social and Carmen Ramirez Moncayo for receiving a 2024 Victoria’s Secret Global Fund for Women’s Cancers Career Development Award, in partnership with Pelotonia & AACR. This award will help fund research on drug resistant ovarian cancer. lms.mrc.ac.uk/aarc-grant/
- Really excited and grateful to receive this funding from @theaacr.bsky.social, which will allow Carmen and I to continue working on the molecular basis and consequences of heterogeneous #PARPinhibitor distribution in #ovariancancer ...first paper on this hopefully coming soon - watch this space!
- 🎉 Congratulations @louisefets.bsky.social and Carmen Ramirez Moncayo for receiving a 2024 Victoria’s Secret Global Fund for Women’s Cancers Career Development Award, in partnership with Pelotonia & AACR. This award will help fund research on drug resistant ovarian cancer. lms.mrc.ac.uk/aarc-grant/
- Wow, predatory journals now asking for WhatsApp numbers?? Has anyone else had this? A whole new level of creepy
- Reposted by Louise FetsWe have a very cool (I know I am biased😁) project for a computational biologist (postdoc) interested in cancer evolution in collaboration with Nicky McGranahan’s lab! Perfect opportunity to expand your computational skills too! 👉 www.godinholab.com RT please 🙏🙏🙏👍👍
- Reposted by Louise FetsThe deadline for abstract submissions and discounted early bird tickets for our upcoming #INTERPHACE2025 symposium is this Friday 13 December 📅 The symposium aims to foster collaboration between experimental and theoretical/computational life sciences. www.crick.ac.uk/whats-on/int...
- Save the date!! the BACR 65th Anniversary Meeting will be held in Edinburgh next June (2nd-4th) and has a broad focus so there is something for everyone in the cancer field. Registration opens January. Please help spread the word!
- Reposted by Louise FetsHear about our research @mrc-lms.bsky.social on digital heart health from BBC World Service (near the start) www.bbc.co.uk/programmes/p...
- Fantastic day celebrating the science of @mrc-lms.bsky.social held at the beautiful Royal Institution. Thank you for all the inspiring talks, proud to be part of this great community!
