Check out the latest from Alan Davidson’s lab (of zf kidney regeneration fame) showing somites contribute to making nephrons in zebrafish. GESTALT, Cre lineage tracing, and zf somite transplants 😱. Love a good story that challenges dogma. Great discussions were had!
www.biorxiv.org/content/10.1...
Somites are a source of nephron progenitors in zebrafish
For over a century it has been believed that the vertebrate kidney arises exclusively from the intermediate mesoderm. Here, we overturn this paradigm by demonstrating that some nephrons, the functiona...
