Luke Gamon
All things teammassspec/realtimechem. Survives on only the fanciest coffee and beer.
Laser capture microdissection | spatial proteomics | protein modification | atherosclerosis | inflammation and oxidation
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- HA! I’m getting trolled at the floor Christmas party. TBH I’d be shocked if everyone didn’t guess this one though. I’m clearly the only person obnoxious enough to walk up and down the corridor hand-grinding coffee beans.
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- Reposted by Luke GamonExcited to share our work at @natcomms.nature.com We used single cell proteomics to define the functional heterogeneity of human neutrophils in glioblastoma, finding pro and anti-tumorigenic effector states invisible to scRNAseq. SCP will revolutionise immunology, this is just the start
- Happy to share our latest preprint doing low cell number (mini-bulk) and single cell #proteomics on tumour associated neutrophils from human glioblastoma where we find multiple functional states that would be invisible to scRNAseq, some showing pro-tumoural states with potential therapeutic value
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- I have now officially been at KU for longer than my previous longest running job (8.5yrs, which I started at age 16). Raised through the ranks from cleaning popcorn and melted ice cream under cinema seats - all the way to projectionist and duty manager. Who knows… could be here another 8.5? 🥼🧪🔬🧫
- Quick heads up - there will soon be a job posting for a Staff Scientist / Senior Staff Scientist in our lab in Copenhagen to support all our mass spec proteomics adventures! Great colleagues, lots of cool projects… and you’ll get to work with me 😅 Please DM if you’re interested!
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- Wow. This is a new one for me. Reviewer 1: ‘Laser capture microdissection leads to a substantial loss and cautheristion of tissue and proteins.’ You’d think citing the top spatial + DVP papers, as well as our own preprint should have been enough for project feasibility 🤦♂️
- Does anyone know how DIA-NN handles isomers? Eg phospho would be the classic example where you have +1phos but could be on two different residues giving peptides with the same m/z but different retention time and fragmentation pattern. What if you don’t have MSMS to separate them?
