- Another #preprint: "Elasticity and plasticity of epithelial gap closure", from the #PhD work of Maryam Setoudeh: arxiv.org/abs/2509.05110 This one required a lot of (I think) beautiful #mechanics! @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
- Epithelial gap closure is a key tissue movement during #development, needing cell rearrangements at the gap edge. To understand the interplay of these plastic cell intercalations with the tissue elasticity, we study a minimal model of a circular gap bounded by a contractile cable in a flat tissue.
- Our work is motivated by Tribolium serosa closure, a particularly simple instance of epithelial gap closure: nature.com/articles/s41467-020-19356-x @akanksha-jain.bsky.social @paveltomancak.bsky.social discovered tissue fluidisation near the gap and inhomogeneities of the contracting cable.
Sep 8, 2025 07:51