labsantoro
We study #epigenetics, #chromatin, #3Dgenome organization and the role of #nucleolus in stem cells and cancer. University of Zurich. https://www.santorolab.org
- Reposted by labsantoroStress controls epigenetic inheritance! A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer 👉 nature.com/articles/s41586-025-09899-8
- Reposted by labsantoroExcited to share our new publication introducing NoLMseq, a method based on laser microdissection of individual nucleoli that enables single-cell mapping of genome-nucleolus interactions across development and under cellular stress. www.nature.com/articles/s41...
- Finally out! We introduce NoLMseq, a #nucleolus laser microdissection method to capture single-cell genome-nucleolus interactions in normal and stressed nucleoli, revealing novel insights into genome organization & function. www.nature.com/articles/s41...
- Reposted by labsantoroExplore RNA's role in epigenetics, DNA repair, transcription & genome organisation - directly with leaders from academia & industry at #GenReg26! Remaining talks to be filled from submissions - register & submit by 04 Sep 2025 to join us in Mexico. Speakers, details & registration➡️ bit.ly/46JQbze
- Very excited to share our latest work in #MolCell showing NPM1 stabilizing the association of nucleolus associated domains (NADs) and recruiting G9a to establish their repressive chromatin states. www.sciencedirect.com/science/arti...
