Kosuke Takada
Postdoc in Eddie’s lab @ USYD | Virology | Evolution
- Reposted by Kosuke TakadaExtremely interesting paper - HA subtypes have wildly different sequences, but share structure and function. Deep mutations scanning of H3, H5, H7: ~50% of HA sites have very diverged preferences for different amino acids 👉 www.biorxiv.org/content/10.6...
- Reposted by Kosuke TakadaNature research paper: Assessing phylogenetic confidence at pandemic scales go.nature.com/3WZMsaV
- We’ve identified a highly divergent betacoronavirus from South American bat that encodes a functional furin cleavage site. Another fascinating reminder of how diverse coronavirus evolution is in wildlife reservoirs. #Virology #VirusEvolution #Bats #Coronavirus www.biorxiv.org/content/10.1...
- Reposted by Kosuke TakadaThere’s been a bunch of new approaches looking at deep viral evolutionary history. We’ve put together a mini review highlighting some recent advancements in structural phylogenetics and time-dependent rate models and what they could do for the field 🦠 🔗 journals.asm.org/doi/full/10....
- Reposted by Kosuke TakadaI’m so excited to finally have this work published. Fantastic work from @julienmelade.bsky.social culturing a virus identified through metagenomic virus discovery methods
- First isolation of a mammalian chuvirus, bizarrely from Tasmanian Devil facial tumour cells. Work led by @julienmelade.bsky.social and @erinharvey.bsky.social. www.sciencedirect.com/science/arti...
- Luthfi did great work on H1N1pdm influenza viruses (isolate strains in 2016–2019)—proud to support his research! www.nature.com/articles/s44...
- Reposted by Kosuke TakadaExcellent, epic review of HPAI H5N1! 👉 www.nature.com/articles/s41...
- Reposted by Kosuke TakadaRhys and I found some weird influenza B viruses in fish a few years ago. For 2, the HA's bind a2,3 sialic acid ("bird type receptor"). The Siamese algae eater virus NA has a highly conserved structure and active site. No cross-reactive antibodies in human sera. 👉 biorxiv.org/content/10.1...
- Reposted by Kosuke TakadaRecombination between positive-sense and negative-sense RNA viruses: journals.plos.org/plospathogen...
- 【My first achievement at Eddie Lab in 2025】 “Genome sizes of animal RNA viruses reflect phylogenetic constraints” doi.org/10.1093/ve/v...
- 【My Key Achievements in 2024】 “Influenza B viruses are more susceptible to high temperatures than influenza A viruses” doi.org/10.1038/s442...
- 【My Key Achievements in 2024】 “Metagenomic analysis of the gut microbiota of hooded cranes (Grus monacha) on the Izumi plain in Japan.” doi.org/10.1002/2211...
- 【My Key Achievements in 2024】 “Genes involved in the limited spread of SARS-CoV-2 in the lower respiratory airways of hamsters may be associated with adaptive evolution.” doi.org/10.1128/jvi....