Kentsis Research Group
Human biology and cancer therapeutics group @MSKCancerCenter
+ @WeillCornellGS + @TPCB_NYC + @TriIMDPhD | + a bit of @oleg8r | Views our own | https://alexkentsis.net
- A transposase-derived gene required for human brain development | Science Advances www.science.org/doi/10.1126/...
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- Reposted by Kentsis Research GroupA summary of training, fellowship, and career development awards Fiscal year 2025 (compared to fiscal year 2024) 1/12
- Developmental Mutators: A unified theory of why young people develop cancer ☛ alexkentsis.net/lecture-deve...
- Reposted by Kentsis Research Group@kentsisresearch.bsky.social develop a proteogenomics workflow to detect 1000s of unknown cancer proteins. PG3 combines long-read RNA sequencing with multi-protease MS to discover non-canonical proteins in cancer cells. Used a timsTOF HT, nanoElute 2 & Aurora Ultimate 25x75 column: bit.ly/4mlQSmu
- Reposted by Kentsis Research GroupA deep dive into the destruction of US cancer research by @jonathanmahler.bsky.social “It’s an absolutely unmitigated disaster,” a former top official at NIH told him. “It will take decades to recover from this, if we ever do.” Gift link: nyti.ms/48iH3Cr
- Listen to my new lecture "Developmental mutagenesis: A unified theory of why young people develop cancer" as part of @stjude.bsky.social @stjuderesearch.bsky.social Science of Childhood Lecture Series on September 18, 2025: www.linkedin.com/events/73719...
- Reposted by Kentsis Research GroupThese are the most challenging times for early-career scientists and engineers. My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers. We found 437 of them. Download it freely here: research.jhu.edu/rdt/funding-...
- Reposted by Kentsis Research GroupPatterns in genomic mutations among patients with early-onset colorectal cancer: an international, multicohort, observational study - The Lancet Oncology www.thelancet.com/journals/lan...
- Reposted by Kentsis Research GroupNEW pub: The role of metabolism in shaping #enzyme structures over 400 million years. Now out in @nature.com Super grateful to have played a small role in this project - congrats to lead/corr authors Oliver, Benjamin, and Markus! www.nature.com/articles/s41... #alphafold #evolution #genomics
- Reposted by Kentsis Research GroupOut in Cell @cp-cell.bsky.social: Design principles of cell-state-specific enhancers in hematopoiesis 🧬🩸 screen of fully synthetic enhancers in blood progenitors 🤖 AI that creates new cell state specific enhancers 🔍 negative synergies between TFs lead to specificity! www.cell.com/cell/fulltex... 🧵
- Supporting medical science in the USA - The Lancet www.thelancet.com/journals/lan...
- What would the National Cancer Act look like today? Bravo Kevin Cullen! Act! cancerletter.com/guest-editor...
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- A new KRG study led by Sumiko Takao @naturecomms.bsky.social uncovers how epigenetic mechanisms control human leukemia stem cells (LSCs) that fuel therapy resistance in AML. www.nature.com/articles/s41...
- A little lab fun
- Reposted by Kentsis Research GroupI am thrilled to share our story online at @cellpress.bsky.social . Big thanks to all authors: Zhiping, Bill, @lubanlab.bsky.social, Keith & bluesky-less! authors.elsevier.com/c/1kjdaL7PXu... How to tame a genome invader? It takes wild koalas 🐨🐨 to learn it. #Retrovirus #koala #piRNA More below 👇
- After many years of explaining trainees how to review scientific manuscripts well, I've summarized them here: docs.google.com/document/d/1...
- Reposted by Kentsis Research GroupTelomeric transposons are pervasive in linear bacterial genomes | Science www.science.org/doi/10.1126/...
