Jakob Trendel
Postdoc in Küster lab at Technical University of Munich (TUM), Germany. Protein-nucleic acid interactions & photo-Xlinking proteomics | RNA | mass spectrometry | RNA-interacting proteomes | DNA-interacting proteomes | nucleotide-crosslinked peptides
- Reposted by Jakob TrendelNew preprint: We isolate peptide–RNA photo-crosslinks with tunable RNA chains from living cells for mass spec. This maps over 4,700 crosslinking sites across 744 proteins and offers the first glimpse into the RNA sequences in crosslinks by MS. Read here: doi.org/10.1101/2025...
- Reposted by Jakob Trendel[Not loaded yet]
- Reposted by Jakob Trendel🚨Our new paper is online🚨 We use zero-distance⚡photo-crosslinking⚡to reveal direct protein-DNA interactions in living cells, enabling quantitative analysis of the DNA-interacting proteome on a timescale of minutes. #DNA #Chromatin #Proteomics www.cell.com/cell/fulltex...
