Jeff Leek
Dad/Coach
Chief Data Officer, Fred Hutch hutchdatascience.org
Professor, Fred Hutch jtleek.com
Founder, Synthesize Bio synthesize.bio
Building things to help people.
Opinions & content are my own.
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- We are really interested in hearing the trainee experience - would love to hear from any trainees about their interests and styles of learning! Check this out and please share!
- The ITCR Training Network (ITN) www.itcrtraining.org develops training materials for informatics and research. We have a short survey ~3-9 min about your experience & preferences for learning as a researcher. Previous engagement not required! xiar7j-itn.shinyapps.io/itn_follow_up/
- Reposted by Jeff LeekThe ITCR Training Network (ITN) www.itcrtraining.org develops training materials for informatics and research. We have a short survey ~3-9 min about your experience & preferences for learning as a researcher. Previous engagement not required! xiar7j-itn.shinyapps.io/itn_follow_up/
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- A cool story that connects the first data I ever analyzed to the work we are doing with Synthesize ! youtube.com/shorts/zN4_m...
- Generative genomics predicts future and impossible experiments! Read the new preprint from Synthesize Bio: www.biorxiv.org/content/10.1... and anyone can try our models on the cloud or in R/Python! product.synthesize.bio
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- Honored to see the Cancer AI Alliance included on TIME's list of the TIME100 AI of 2025! #TIME100AI. CAIA has been a true team sport based on the shared commitment of all our Alliance members to accelerate cancer research and ultimately improve and save patient’s lives. time.com/collections/...
- Check out this great post explaining our approach to enabling AI model learning and reasoning across multiple-institutions while carefully protecting (and never transferring!) patient data! www.canceralliance.ai/blog/caia-fe...
- I was recently on a panel talking about Synthesize Bio and the future of AI in biotech! www.youtube.com/watch?v=AR5s...
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- Code from my first live R package demo talk in honor of Hadley at #jsm2025 gist.github.com/jtleek/8c927... Steve Salerno, Awan Afiaz, and I have been developing the scorcher package to help you more easily fit deep learning models in R ! github.com/jtleek/scorc...
- The highlight of my #jsm2025 talk was @hadley.nz roasting the panel with ChatGPT.😂 I also love that he talked about aspiring to kindness!
- We are about to be live talking about how cool @hadley.nz is in CC214 at 1030am ! Come hang out if you are at #jsm2025
- My family and I are going to be running the 5k at Obliteride again this year! (we'll be biking as soon as the boys are old enough :)). We are raising funds for data science and AI efforts to find cancer cures at the Fred Hutch, consider donating if you are able! secure.fredhutch.org/site/TR/Obli...
- Wild congratulations to one of the most incredible people I’ve ever worked with. @benlangmead.bsky.social I hope you are celebrating this very well deserved honor!!!
- These are not just grants. This is thousands of people who devoted their lives and careers - taking pay cuts, working long hours, living with uncertainty - all for the chance to try to make people's lives a bit better for you and your loved ones. This breaks my heart.
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- Reposted by Jeff LeekIndustry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.
- If you are around Seattle, see ya there :)
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- NOOOOOOOOOOOOOOOOOOOOOO
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- Synthesize Bio's platform is awesome as a teaching tool. In just a couple of minutes you can (a) find a dataset, (b) run a validated workflow like @mikelove.bsky.social's published EDA workflow, and (c) share with your friends: app.synthesize.bio/notebooks/3a...
- Reposted by Jeff LeekThis alliance helps solve the key technical challenges that will enable us to securely use both #AI and massive computational power to find these breakthrough insights and save more lives. Congrats to the CAIA team on this well-deserved recognition! #oncsky
- Congrats to the Cancer AI Alliance (CAIA) on being named @geekwire.com's Health Innovation of the Year! This Fred Hutch-led initiative unites experts to apply responsible #AI to cancer centers’ data, unlocking insights while ensuring data security. Learn more: www.canceralliance.ai
- An incredible honor and the momentum is building for the Cancer AI Alliance. We have been hard at work behind the scenes - expect more public from us soon! @brianmbot.bsky.social (pictured) and the broader CAIA team are amazing and it is fantastic to see their work rewarded.
- Congrats to the Cancer AI Alliance (CAIA) on being named @geekwire.com's Health Innovation of the Year! This Fred Hutch-led initiative unites experts to apply responsible #AI to cancer centers’ data, unlocking insights while ensuring data security. Learn more: www.canceralliance.ai
- Reposted by Jeff LeekWe are in a period of remarkable progress in cancer research and care. It’s critical that we don’t let near-term pressures immobilize us and lose sight of our long-term plans. Thanks to Becker’s Hospital Review for inviting me to share what's at stake. www.beckershospitalreview.com/oncology/ami...
- Really excited about releasing our platform for integrating gene expression data - search for and easily integrate multiple datasets app.synthesize.bio/datasets, analyze them in Notebooks, and sign up for our beta for AI-generated gene expression data from experimental designs!
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- This is beyond short sighted. www.science.org/content/arti... The Women’s Health Initiative is simultaneously a gold standard for how to do large scale research, a huge impact study, a long term investment, and one of the best resources for AI in science. I’m just gutted for everyone involved
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- The Cancer AI Alliance (www.canceralliance.ai) is hiring for a full time Director of Operations role careers-fhcrc.icims.com/jobs/29460/c... This role will drive execution across legal, financial, research compliance, philanthropy, and business development.
- Reposted by Jeff Leekwww.nytimes.com/2025/04/03/o... Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
- Excited to officially welcome Google and AI2 to the Cancer AI Alliance ! www.prnewswire.com/news-release... The alliance is enabling us to move at incredible speed and still being super careful about data thanks to the big collaborative team of experts!
- Check out this awesome new R package for simplifying working with AWS from folks at @fredhutch.bsky.social recology.info/2025/04/sixt...
- Public health biostatistics has always been incredibly important; but in this moment even more so! Consider nominating an early career biostatistician for our field's most prestigious award: www.spiegelmanaward.org by May 1! This is an opportunity to highlight how biostatistics helps so many people
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- Our Cancer AI Alliance is up for Health Innovation of the Year for the Seattle-based Geekwire awards! www.geekwire.com/events/2025-... @fredhutch.bsky.social is very proud to represent our Alliance - we'd love your vote for the hard work being done by all of the people involved!
- Watching one of the world’s leading scientists talk about one of the world’s most important studies; Garnet Anderson from @fredhutch.bsky.social reflecting on 30 years of the Women’s Health Initiative. Such an incredible force for good over 3+ decades
- This is an incredibly important post by @rafalab.bsky.social on our Simply Statistics blog (its still around!) on why "indirect costs" are spent on research and its not enough! simplystatistics.org/posts/2025-0...
- Amazing work from a big collaborative group in publishing our ipd R package for doing inference after prediction. Are you making predictions with ML models? Then you should be using ipd! academic.oup.com/bioinformati... code here: github.com/ipd-tools/ipd
- This is an INCREDIBLE episode. I would say without exaggeration podcast episode of the year in #ai. It is a fully human centered view of the data that drives our models. Should be required listening for anyone who uses data about people in their work.
- So excited about the huge possibilities of this public private partnership with our amazing colleagues in tech and across cancer centers!!
- A terrific recap of my Q&A with @fredhutch.bsky.social chief data officer @jtleek.bsky.social about the Cancer AI Alliance, the transformative potential of #AI in #cancer care and research, and how we can collaborate with other research powerhouses while protecting patient data.
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- I think one low cost, high impact intervention to improve peer review is training trainees on what peer review should look like. I wrote this guide for my students: github.com/jtleek/reviews that includes an opinionated approach to what is/isn't important in review (pretty computationally flavored)
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