Jana Kroll
Postdoc at MDC Berlin
cryo-electron tomography, neurons, optogenetics
- Reposted by Jana KrollPlease share🙏: Our lab opens 2 PhD positions to investigate fungi's evolution: #Barcelona Wet lab in Biochemistry/Structural Biology of cryo-tolerant fungi www.upf.edu/documents/d/... Computational in Physical Chemistry of cellular processes under extrem environments www.upf.edu/documents/d/...
- Reposted by Jana Kroll🔬🔦 Imaging spotlight on FocalPlane @janakroll.bsky.social and colleagues highlight their research visualising synaptic vesicle fusion using cryo-ET combined with plunge freezing and optogenetics. focalplane.biologists.com/2026/01/21/i...
- ❄️ With all the snow outside, I felt like sharing a cryo tomogram: A neuronal synapse, captured by cryo-ET at the moment a neurotransmitter-filled vesicle fuses at the active zone. Fusion was triggered optogenetically and arrested by plunge freezing. More details: www.nature.com/articles/s41...
- Reposted by Jana KrollDer Moment, in dem eine Nervenzelle ihre Neurotransmitter in den synaptischen Spalt ausschüttet, ist extrem kurz. Berliner Forschenden @bihatcharite.bsky.social @mdc-berlin.bsky.social konnten ihn mikroskopisch einfangen. doi.org/10.1038/s414... Bild: © Charité/Max Delbrück Center, Jana Kroll
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- ❄️🔬⏱️ I am excited to share that our study „Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons” has been published in Nature Communications www.nature.com/articles/s41... 👇 Short summary of our key findings (1/8)
- We established a timed in situ cryo-electron tomography workflow to capture the complete sequence of synaptic vesicle fusion in optogenetically stimulated mouse neurons. Using a modified plunge freezer, the "Voptobot", we stimulated neurons only 2-3 milliseconds before cryofixation. (2/8)
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- Reposted by Jana KrollWe got a large Helmholtz Bioengineering grant with Oliver Daumke, Artur Yakimovich, Alina Bazarova, and Dietrich Ruess to use protein design to target cancer. Five open postdoctoral positions in Generative AI & Protein Engineering. Share & apply! jobrxiv.org/job/max-delb...
- Reposted by Jana KrollGroup Leader in Biomedical Engineering at the @mdc-berlin.bsky.social in Berlin. It's a broad call for whoever is doing exciting Bioengineering, please apply or share. We have a great institute with amazing colleagues and core facilities,highly recommend application.mdc-berlin.de/site/index.p...
- Reposted by Jana KrollPostdoc program at the MDC in Berlin, @mdc-berlin.bsky.social : take a look 👇👇 For this call, collaborative projects between two groups will be funded. Take a look at the call and the groups and drop me an email if interested. Share with colleagues too! www.mdc-berlin.de/postdocs#t-g...
- Reposted by Jana Kroll
[Not loaded yet] - Reposted by Jana KrollWe have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...
- What an inspiring morning at the CatCat Symposium! Thank you so much for inviting me @gallegolab.bsky.social and @felixmendu.bsky.social, it's been a pleasure visiting you in Barcelona 😊
- So many amazing images! 🤩 🤩🤩 Please make sure to vote, mine is also in the list 😎
- 🎉 Public Voting Now OPEN – #HelmholtzImaging Best Scientific Image Contest 2025 Choose your favorite(s) & cast your vote by May 30 👉 bit.ly/BSIC2025-Public-Voting The award recipients will be announced at our conference on June 26. #HIBestImage25 #HIConference25 @www.helmholtz.de
- Reposted by Jana KrollA broad call for a PhD researcher/ postdoc in our group at the MDC in Berlin. An ideal PhD student - a computational scientist, a postdoc - a structural biologist, but feel free to re-convince me! We extended the deadline for after Easter, Apr 24th. Apply here www.mdc-berlin.de/career/jobs/...
- Reposted by Jana KrollWe are looking for a PhD student/Postdoc to develop methods of cryo-ET and/or study the structure and function of membrane proteins. Great team at the MDC in Berlin. It's a broad call, please apply and share! jobrxiv.org/job/max-delb...
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- Cryo-confocal microscopy of a neuron expressing the glutamate sensor iGluSnFR 🥶 The neuron was optogenetically stimulated and subsequently plunge-frozen to preserve the high fluorescence intensity indicating neurotransmitter release. #FluorescenceFriday
- Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" www.biorxiv.org/content/10.1... We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️
- First and foremost, thank you @icecoldsynapse.bsky.social, @mohsensadeghi.bsky.social, @mishakudryashev.bsky.social, Christoph, Lia, Gosia, Thiemo, Magdalena and Christian for your contributions!
- It's been a pleasure presenting my project at this fantastic workshop! ☺️ #EMBOinsitu
