IOB - Institute of Molecular and Clinical Ophthalmology Basel
Where Science Meets Vision
At the Institute of Molecular and Clinical Ophthalmology Basel (IOB), our mission is to advance the understanding of vision and its diseases, and to develop new therapies for vision loss.
- 🧬 Major breakthrough: IOB researchers identify new genetic cause of inherited blindness in overlooked RNA genes. The discovery solves decades-old diagnostic mystery and opens new pathways for many patients worldwide. ➡️ www.nature.com/articles/s41... #AcademicBlueSky #Genetics #VisionResearch #IRDs
- 🌟New hope for vision restoration: Congratulations to Bence György on his 5-year @erc.europa.eu Consolidator Grant. His proposal was selected among 3121 applications from across Europe - a strong vote of confidence in our work at IOB! #ERCCoG #BaseEditing #VisionResearch #Blindness #AcademicBlueSky
- 🌟New hope for vision restoration: Warm congratulations to Bence György on his 5-year @erc.europa.eu Consolidator Grant to advance base editing for genetic macular degeneration and explore therapies for corneal blindness. #ERCCoG #BaseEditing #VisionResearch #Blindness #AcademicBlueSky
- 🎉 Big congratulations to @karkam.bsky.social who has just been awarded the PRO RETINA Research Award 2025 for her latest paper in American Journal of Human Genetics! #ResearchAward #AcademicBlueSky #Ophthalmology #MacularDystrophy #Lysosomes #RetinalDisease #VisionResearch #RareDiseases
- New hope for inherited vision loss IOB researchers (@karkam.bsky.social, @carlorivolta.bsky.social, @mquinodoz.bsky.social, @abimoye.bsky.social) identify AP5Z1, AP5M1, AP5B1 mutations, revealing new causes of macular dystrophy. 🔗 www.cell.com/ajhg/fulltex... #AcademicBlueSky #Ophthalmology
- 🚨 CALL FOR APPLICATIONS 🚨 Looking for your next academic step? Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases. ⏰ Deadline: November 16, 2025 (midnight CET) 🔗 iob.ch/phd-md-phd-program #IOB #Basel #PhDProgram #VisionScience
- Can a blind retina be made sensitive to infrared light? Our team shows that an engineered human TRPV1 channel, delivered by AAV, elicits robust responses without foreign proteins or nanoparticles. 🔗 bit.ly/4gt0LO5 #AcademicBlueSky #ProteinEngineering #TRPChannels #SyntheticBiology #Vision #Retina
- 🧬 How can we navigate the genetic complexity of inherited retinal diseases? Our new paper in @ajhgnews.bsky.social presents RetiGene, a curated atlas of IRD genes, built with @erdc-team.bsky.social, to support diagnosis, research and therapy. 👉 bit.ly/467U1S9 #AcademicBlueSky #IRDs #VisionResearch
- 🔬👁️ Organoids in the spotlight! Magdalena Renner, leading IOB’s organoid platform, shares how high-throughput organoid systems are transforming research and speeding up the path to therapies for eye diseases. Read more: bit.ly/4mquwjP #VisionResearch #HistoBrick #Blindness #Retina #AcademicBlueSky
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- Gene editing of single, targeted neurons in vivo is now feasible. We are proud to present our preprint for highly efficient single-cell electroporation using RNA. With @alex-fratzl.bsky.social, @munzlab.bsky.social, Botond Roska @iobswiss.bsky.social #neuroskyence www.biorxiv.org/content/10.1...
- 👏Warm congratulations to our former IOB postdoctoral fellow @fionamuellner.bsky.social on her new role as Group Leader at @dandrite.bsky.social & Associate Professor at Aarhus University — and on receiving a prestigious ERC Starting Grant! @erc.europa.eu
- This changes how we think about vision: timing coordination starts in the eye - not the brain! Check out @anbucci.bsky.social & @ffranke.bsky.social's discovery: nature.com/articles/s41... #Neuroscience #Vision #RGCs #RetinalResearch #AcademicBlueSky #EyeResearch #ScientificDiscovery
- 🧠👁️ How does your eye prevent seeing a scrambled world? @anbucci.bsky.social and @ffranke.bsky.social reveal the eye's secret "clockwork": bigger axons = faster signals = perfect visual timing! 📖 Full paper nature.com/articles/s41593-025-02011-3 #Vision #AcademicSky #Neuroscience #Retina Image ©IOB
- 🚨 We are hiring! IOB is looking for an enthusiastic IT career starter (Level 1 Helpdesk) to join our support team. Whether you are a student, graduate, or making a career change, this entry-level role is a great opportunity to launch your path in IT. Interested? 👉 iob.ch/join-iob/ope... #AcademicSky
- 🧬👁️Discover how research and patient care come together in the latest Novartis Live magazine — with stories from the labs and clinics shaping the future of vision. 🔗 bit.ly/4km6XZ0 #IOB #VisionScience #TranslationalResearch #Basel #Ophthalmology #AcademicSky #Novartis
- 🔬 We are hiring! Research Assistant/Associate (100%) – Molecular Mechanisms of Myopia 📍 Location: Basel 🧪 Background in molecular biology, genomics, neuroscience or related field 💼 Full-time position Apply now or share! iob.ch/join-iob/ope...
- What controls eye growth? 10 key insights from decades of myopia research - from retinal feedback to red light therapy, here is what we know: 🔗 onlinelibrary.wiley.com/doi/10.1111/... #Myopia #VisionResearch #Ophthalmology #GlobalHealth #AcademicBlueSky Image © IOB, generated with Google AI, 2025
- 🧬IOB researchers (@Mukhtarullah.bsky.social @karkam.bsky.social @carlorivolta.bsky.social @mquinodoz.bsky.social) and international team uncover genetic signatures of eye diseases in Pakistan 📖 doi.org/10.1038/s415... #Genetics #Vision #AcademicSky Image © IOB, generated with Google AI, Gemini
- 🧠 Brain efficiency doesn't need perfect organization Random neural responses can lead to better information processing than precisely tuned ones. www.sciencedirect.com/science/arti... @ravadasilveira.bsky.social | image © IOB, 2025 #AcademicSky #Neuroscience #ScienceNews
- New hope for inherited vision loss IOB researchers (@karkam.bsky.social, @carlorivolta.bsky.social, @mquinodoz.bsky.social, @abimoye.bsky.social) identify AP5Z1, AP5M1, AP5B1 mutations, revealing new causes of macular dystrophy. 🔗 www.cell.com/ajhg/fulltex... #AcademicBlueSky #Ophthalmology
- 🧠 How does your brain create mental maps? New research reveals a surprisingly simple mathematical principle behind complex spatial representations! From rodents to bats, same rules apply 🐁🦇 #Neuroscience #BrainScience #ScienceNews #AcademicBluesky Read more here: www.cell.com/neuron/fullt...
- We are thrilled to have contributed to this innovative research published in Advanced Functional Materials, together with the team of @tobiasruff.bsky.social at ETH! Check out the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/... 🧠 #neuroscience #brainresearch #academicsky
- How do different sensory signals combine in the computation of cognitive maps? I’m thrilled to share our new preprint, in which we investigate this question in the context of the head-direction system: www.biorxiv.org/content/10.1...
- 🔍 Did you ever wonder why your eyes make tiny movements even when trying to hold still? Those movements are not a bug, they are an essential feature for sharp vision! Here is why: www.pnas.org/doi/epub/10.... #AcademicSky #Neuroscience #Ophthalmology Illustration ©IOB, 2025
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- 👁️ Advancing Vision Research 👁️ Our latest study with collaborators from CSEM introduces a HistoBrick array made from a novel material mix, optimizing cryosectioning and immunohistochemistry for retinal organoids and small tissues. 📖 Learn more: rdcu.be/d5o8Z #Organoids #AcademicSky Picture © IOB
- We are pleased to share that RhyGaze, IOB's first spin-off, has secured Series A funding with an USD 86 million investment to advance vision restoration therapy. Read more: iob.ch/news-view-al... #Biotech #Basel #Innovation #LifeSciences #GeneTherapy #Ophthalmology #RhyGaze #BioTechHub
- ✨Thrilled about our new publication in Nature Medicine! We are excited to offer a potential new avenue for treating Stargardt disease! Read the paper here: nature.com/articles/s41... Watch the video: iob.ch/fileadmin/ge... Press release here: iob.ch/news-view-al... © 2025 IOB
- ✨Scientific breakthrough: IOB researchers have achieved a significant advance in developing a new treatment for Stargardt disease, the most common form of inherited macular degeneration. Read more: www.nature.com/articles/s41... Watch full movie: iob.ch/news-view-al... #AcademicSky #neuroscience
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