Finn Lueth
bioinformatics @TU_Muenchen | undergrad researcher @rostlab
(ᴅʀᴜɢs, ᴘʀᴏᴛᴇɪɴs) × ᴍʟ | 𝘯𝘢𝘵𝘶𝘳𝘢 𝘢𝘳𝘵𝘪𝘴 𝘮𝘢𝘨𝘪𝘴𝘵𝘳𝘢.
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- Easy and interactive taxonomic profiling with Metabuli App. It integrates database curation, read QC, taxonomic profiling, and visualization right on your desktop. No command line, server, or internet required. Now published in Bioinformatics! 🧵1/5 doi.org/10.1093/bioi... github.com/steineggerla...
- Tomorrow we have a reading group session with @nscorley and @SimMat20 about "Accelerating Biomolecular Modeling with AtomWorks and RF3" www.biorxiv.org/content/10.1... We will also discuss how to close the gap between AF3 and its open source replications! portal.valencelabs.com/starklyspeak...
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- My new paper "Deep Learning is Not So Mysterious or Different": arxiv.org/abs/2503.02113. Generalization behaviours in deep learning can be intuitively understood through a notion of soft inductive biases, and formally characterized with countable hypothesis bounds! 1/12
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- @maxhenrybarnhart.bsky.social has written a really nice piece on BioEmu for Chemical & Engineering news. cen.acs.org/biological-c...
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- Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco
- AlphaGenome deepmind.google/discover/blo... 🧬🖥️🧪 API: github.com/google-deepm... Docs: www.alphagenomedocs.com Community: www.alphagenomecommunity.com
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- Thank you everyone for attending the Boltz-2 Boston, San Francisco and Paris events this week! Given the success of the in-person seminars and the many requests, we are organizing a virtual seminar on Tuesday at 12pm ET / 6pm CET! Sign up here: lu.ma/4bpuwbsr
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- Visit our posters at #RECOMB2025 for: Structural: MSAs, Virus DB, Core Genes, Motif Discovery, Multimer Clustering & Search, pLM Foldseek, Environmental analysis Metagenomics: Classification & Metabuli App GPU-based & RNA search, Proteome clustering, Novel Ribozyme discovery & get Marv stickers!
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- We trained a genomic language model on all observed evolution, which we are calling Evo 2. The model achieves an unprecedented breadth in capabilities, enabling prediction and design tasks from molecular to genome scale and across all three domains of life.
- Protein dynamics was the first research to enchant me >10yrs ago, but I left in PhD bc I couldn't find big experimental data to evaluate models. Today w @ginaelnesr.bsky.social, I'm thrilled to share the big dynamics data I've been dreaming of, and the mdl we trained w them: Dyna-1. 📝: rb.gy/de5axp
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- Thank you so much for integrating Foldseek into the great ChimeraX.
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