Fabrice Jean-Pierre
Assistant Professor @USherbrooke | Polymicrobial biofilms, interactions & mechanisms of recalcitrance | he/him
fjplab.com
scholar.google.ca/citations?user=N5Ul…
- Reposted by Fabrice Jean-PierreNew paper out! Here's a puzzle: phototrophy, the ability to use light for energy, is one of life's great innovations. It evolved early and transformed the biosphere. But it evolved 2x. Why not just once, why not more? Our work suggests the answer is priority effects. www.nature.com/articles/s44...
- Reposted by Fabrice Jean-Pierreglad so many of you *like* the 𝘝𝘢𝘮𝘱𝘺𝘳𝘦𝘭𝘭𝘢 having lunch 🙂 but don't miss the recent work of beryl rapaport et al. on another amoeba, 🔥 𝘐𝘯𝘤𝘦𝘯𝘥𝘪𝘢𝘮𝘰𝘦𝘣𝘢 𝘤𝘢𝘴𝘤𝘢𝘥𝘦𝘯𝘴𝘪𝘴 🔥dancing at 63°C on STC 👉 smallthingsconsidered.blog/schaechter/2...
- #ProtistsOnSky no 'swimming' by 𝘝𝘢𝘮𝘱𝘺𝘳𝘦𝘭𝘭𝘢, definitively no 'staying still'. just a relaxed walk towards the lunch...
- Abstract submission deadline for the 2026 Eurobiofilms meeting is approaching! For more info see link below. #microsky #biofilms eurobiofilms2026.org
- Cool stuff! “A quorum-sensing molecule from Pseudomonas aeruginosa induces defensive multicellularity in a coinfecting pathogen” #microsky
- Reposted by Fabrice Jean-PierreLactic acid lover? Check out @ronni.bsky.social 's new work in @cp-cellhostmicrobe.bsky.social showing how Enterococcus faecalis-derived LA suppresses macrophage activation, in turn promoting bacterial persistence and polymicrobial wound infection in vivo. www.sciencedirect.com/science/arti...
- Sigh. Will Pseudomonas aeruginosa be the next victim? #microsky
- How do you react when your favorite microbe is renamed by taxonomists who are completely outside your field—and who ignore the community that actually works with it? Here is our clear answer re the case of Pseudomonas putida KT2440 👉🏻 journals.asm.org/doi/10.1128/...
- Reposted by Fabrice Jean-PierreHow do you react when your favorite microbe is renamed by taxonomists who are completely outside your field—and who ignore the community that actually works with it? Here is our clear answer re the case of Pseudomonas putida KT2440 👉🏻 journals.asm.org/doi/10.1128/...
- Reposted by Fabrice Jean-Pierrewww.pnas.org/doi/10.1073/... Excited to share that PNAS published our research article focused on "Why are Ralstonia goofy?"
- Reposted by Fabrice Jean-PierreNew in JB: Khan, Palmer & Guan identified the genes for glucosaminyl phosphatidylglycerol biosynthesis, opening the way to study this lipid in P. aeruginosa. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Reposted by Fabrice Jean-PierreApplication deadline for this postdoc position in my group closing next week 🦠 thank you all who have shared so far!
- 🔊 Job Opportunity: Postdoctoral Research Fellow in Bacterial Evolution. Looking to recruit a postdoc to join a UKRI FLF-funded project on antibiotic resistance evolution in the microbiome 🦠 3 years funding, deadline 26th Jan, please share! hrwebapp.qub.ac.uk/tlive_webrec...
- The School of Life Sciences at the University of Nevada, Las Vegas invites applications for a tenure-track Assistant Professor in Cell and Molecular Biology. Please share! #microsky
- Reposted by Fabrice Jean-Pierre🚨4-year fully funded PhD in the lab of @magicmicrobe.bsky.social (& collaborating with me!): How does iron availability shape the ability of pathogens to invade the gut microbiome? Apply by Jan 26th Advert: research.reading.ac.uk/foodbiosyste... How to apply: research.reading.ac.uk/foodbiosyste...
- Cool work! #microsky
- Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis @natcomms.nature.com by @harisantypas.bsky.social et al from @kimingeneva.bsky.social www.nature.com/articles/s41...
- Reposted by Fabrice Jean-PierreSummer REU in biofilms! Pls share. www.binghamton.edu/centers/biof...
- Reposted by Fabrice Jean-PierreGrinnell College has openings for two 1-year term positionsto teach microbiology and immunology. More information here: apply.interfolio.com/179939
- Reposted by Fabrice Jean-PierreJB Editor's Choice: Galyon, Atomi & Santangelo describe the history of Thermococcales as a model system, & where the field is going. A great primer for this organism. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology See our whole Model Systems collection! journals.asm.org/topic/sss-ta...
- Reposted by Fabrice Jean-PierreJB Editor's Choice: Morales Moreira, Haney et al. explore the conservation of genes required for production of the nitroimidazole antibiotic azomycin, made by a variety of pseudomonads. And show that this compound can kill omycete pathogens. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Reposted by Fabrice Jean-PierreHow does E. coli age? According to this #mBio study, the the decisive factor driving growth decline in E. coli is not the presence of protein aggregates, but the fraction of the intracellular space they occupy. Learn more: asm.social/2KZ
- Reposted by Fabrice Jean-PierreCongratulations to Sean Yu-Hao Wang, Will DePas, @catarmbruster.bsky.social and colleagues on their use of experimental evolution to identify regulators of Mycobacterium abscessus biofilm production! www.sciencedirect.com/science/arti...
- Reposted by Fabrice Jean-PierreJust in time for the holidays, the newest issue of JB is out! We have reviews on cobamide synthesis and QS, and Thermococcales as a model system. Check out articles on methanogenic archaea, C. trachomatis, Peudomonads, Staph, C. diff & more! journals.asm.org/toc/jb/207/12 @asm.org #JBacteriology
- “Microbiota, Mucus, and Modulators: CF Infection Pathogenesis in the CFTR Modulator Era” #microsky
- Reposted by Fabrice Jean-PierreNew in JB: Chan, Guo et al. explore the role of membrane vesicles produced under different in protecting Enterococcus faecalis from stress and immune cells. This work links changing pH to resistance in the infection environment. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Reposted by Fabrice Jean-PierreThis is a disaster. I would not be where I am today without the constructive (and yes, sometimes frustrating) reviews my NSF proposals received as a young investigator. This feedback didn't come from the POs but rather the peer reviewers and panelists who saw how I was trying to enter the field
- Reposted by Fabrice Jean-PierreNew in JB: Trottier, Déziel et al. show that despite the conservation of the PqsE sequence of P. aeruginosa and some key conserved functions, including and essential role for HAQ biosynthesis, this protein has different impacts across strains of Pa. journals.asm.org/doi/10.1128/...
- Reposted by Fabrice Jean-PierreThe 2025 Agar Art Contest winners have been selected! This year’s theme, “Microbes Make the World Go Round,” inspired 557 global entries—from food fermentation to antibiotic production. See the masterpieces and finalists! asm.org/press-releas... #agarart
- Reposted by Fabrice Jean-PierreExcited to announce that Shawna Pratt, a postdoc in the lab, has been awarded an American Heart Association Postdoctoral Fellowship to pursue her studies of biofilm formation at the interface of engineering and microbiology. Congrats Shawna!
- Reposted by Fabrice Jean-PierreNew in JB: Price & Skaar explore the role of metals in biofilm biology with an eye on how to use this information therapeutically. I love the title: "Forging biofilms: metal-induced microbial responses in biofilm formation" journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Reposted by Fabrice Jean-PierreNew in JB: Roman-Rodriguez, Boyd et al. show that in the battle between P. aeruginosa and S. aureus, Staph can adapt to HQNO-mediated targeting of its respiratory pathway by increasing flux thru its fermentative pathways. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Reposted by Fabrice Jean-PierreNew in JB: Dietrich Nies reviews the mechanisms that bacteria use to control metal homeostasis and prevent mismethylation using zinc as a model metal and Cupriavidus metallidurans as the model microbe. (always fun to see a single author pub!) journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- “Transcriptional and metabolic modeling analyses of developing Aspergillus fumigatus biofilms reveal metabolic shifts required for biofilm maturation” #microsky
- Reposted by Fabrice Jean-PierreIn a manuscript on BioRxiv, we describe experiments exploring the culturome of the gut of adults with CF and in health, revealing an interesting redistribution of the microbes in the lumen vs. mucosa. The study is led by Sarvesh Surve a PhD student in my lab. www.biorxiv.org/content/10.1...
- Reposted by Fabrice Jean-PierreJB Editor's Choice: Anderson, Khursigara et al. review the role of peptidoglycomics in understanding the structure and function of peptidoglycan. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Reposted by Fabrice Jean-PierreExcited to share our new work comparing the impact of long-term CFTR modulator therapy on #CF lung pathogens & respiratory microbiome within a large, multi-centre & multi-national cohort of adults living with #cysticfibrosis www.medrxiv.org/content/10.1...
- Reposted by Fabrice Jean-PierreMetabolic interplay drives population cycles in a cross-feeding microbial community @natcomms.nature.com from @oventurelli2.bsky.social www.nature.com/articles/s41...
- Reposted by Fabrice Jean-PierreJB Editor's Choice: Endres, Lehman et al. use a cool genetic selection to help identify 4 different pyruvate transporters in S. aureus, indicating the importance of this substrate for this microbe. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- “CFTR modulator therapy drives microbiome restructuring through improved host physiology in cystic fibrosis: the IMMProveCF phase IV trial” #microsky www.nature.com/articles/s41...
- Reposted by Fabrice Jean-PierreExcited to share new work from Sarvesh Surve examining the gut microbiota of adults with CF using colonoscopy samples and a culturomics approach. We note continued depletion of Bacteroidota (which we noted in kids) & enrichment of aerobes in the mucosa of pwCF. pubmed.ncbi.nlm.nih.gov/41256617/
- Reposted by Fabrice Jean-PierreThe newest issue of JB is out! This month's issue has article on topics including bacterial pseudo-receiver domains, B. frag/B.theta as model bugs, peptidoglycomics, pyruvate transport in Staph, "swashing" motility, and more! Check it out! journals.asm.org/toc/jb/207/11
- Reposted by Fabrice Jean-PierreHot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/ www.science.org/doi/10.1126/...
- Reposted by Fabrice Jean-PierreApply now to attend the next EMBO Bacterial Networks meeting #EMBOBacNet 🗓️13-18 September 2026 📍Sant Feliu de Guixols, Spain 📝Program and registration info: meetings.embo.org/event/26-bac... 👩🔬Organised with co-chair @s-lab.bsky.social and ECR @coralietesseur.bsky.social #MicroSky
- Reposted by Fabrice Jean-PierreWhy does daptomycin resistance appear so fast in Enterococcus? We finally have a clue. DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
- Reposted by Fabrice Jean-PierrePls share: HHMI - Program Officer - Science Education Alliance hhmi.wd1.myworkdayjobs.com/en-US/Extern...
- We're hiring! My dept. is looking for a candidate with a research program focusing on plant systems. All areas of molecular and cellular biology research will be considered. Not sure if you'd fit? Reach out to me. Please share! #microsky
- Reposted by Fabrice Jean-PierreBacteria export alarmone synthetases that produce (p)ppApp and (p)ppGpp 🦠🤯 From Boyuan Wang and John Whitney journals.asm.org/doi/10.1128/...
- Thanks, George!
- A really nice profile of Fabrice Jean-Pierre, a former postdoc in the lab doing great work in his own lab at the University of Sherbrooke. Congrats Fabrice! cysticfibrosis.ca/blog/dr.-fab...
- Reposted by Fabrice Jean-PierreGac Is a Transcriptional Repressor of the Lyme Disease Spirochete's OspC Virulence-Associated Surface Protein Castro-Padovani, Saylor, Husted, Krusenstjerna, Jusufovic, and Stevenson 2023, J Bacteriol, 205:e0044022. doi: 10.1128/jb.00440-22 pubmed.ncbi.nlm.nih.gov/36920207/ #MicroSky
- "Functional CFTR may be required for Prevotella melaninogenica regulation of epithelial cell defense against Staphylococcus aureus" pubmed.ncbi.nlm.nih.gov/41198444/ #microsky
- Reposted by Fabrice Jean-PierrePrevotella is the clear favorite of the 4-member cookie community (not like I’m surprised) @bassamhafi.bsky.social @fabricejpierre.bsky.social
- Reposted by Fabrice Jean-PierreAn update on my column: Parliamentary committee drops most contentious parts of its demand for data on research funding. It now wants aggregated, not disaggregated data. www.theglobeandmail.com/opinion/arti...
- How much are MPs entitled to know about research grants? Not as much as they think. A parliamentary committee is asking for researchers' personal information in what seems like an anti-DEI crusade, by @picardonhealth.bsky.social www.theglobeandmail.com/opinion/arti... via @theglobeandmail.com
- Le BiSP/Micrhub est sur le point de débuter à @usherbrooke.bsky.social ! Deux jours de microbiologie/bactériologie seront à l’honneur en plus d’avoir deux keynotes @lalouxlab.bsky.social et @bjesseshapiro.bsky.social. Nous avons hâte de vous accueillir! @micrhub.bsky.social #microsky
- We should be paying more attention to this situation. An online letter has been put together and is being circulated to stop this data from being disclosed. Please sign the online letter here, if you are comfortable: docs.google.com/forms/d/e/1F...
- a gross parliamentary overreach — article by @picardonhealth.bsky.social in the globe and mail; #academicsky #neuroskyence #psychscisky www.theglobeandmail.com/gift/91587b9...
- Reposted by Fabrice Jean-PierreThe 10th ASM Conference on Biofilms is one week away in Portland, Oregon (11/09-13/25)! Looking forward to seeing many biofilm community members and catching up on the amazing research underway in labs around the world! There is still time to register! #ASMBiofilms
- Reposted by Fabrice Jean-PierreNew in JB: A minireview from my team, led by a recently graduated PhD student Kaitlyn Barrack, compares the microbiota and physiology of the CF gut with features of the gut in inflammatory bowel disease - there are many similarities! journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Lots of fun in the Bio dept @usherbrooke.bsky.social today! Pumpkin carving and best Halloween costume competition across labs. Can you guess our lab’s costume theme? #microsky
- Reposted by Fabrice Jean-Pierre
Canadian researchers should be aware the there is a motion before the Parliamentary Standing Committee on Science and Research to force Tricouncils to hand over disaggregated peer review data on all applications: Applicant names, profiles, demographics Reviewers names, profiles, comments, and scores - Reposted by Fabrice Jean-PierreO'Toole lab alum doing well at NACFC! Fabrice Jean-Pierre led the session on polymicrobial infections in CF and Rebcca Valls gave a talk that was a top 5 finalist for best jr abstract! Great to see DartCF people doing so well!
- Had a blast attending #NACFC2025 in Seattle this year! Had the chance to organize and co-chair a session on microbial communities and polymicrobial interactions. A big bonus is having the opportunity to catch up with friends. #microsky #cysticfibrosis
- Reposted by Fabrice Jean-PierreCome be my colleague! We have new faculty searches in Virology & Fungal Biology/Medical Mycology. UMN has great people & the Twin Cities are beautiful year-round! Virology: hr.myu.umn.edu/jobs/ext/365... Fungal Biology / Medical Mycology: hr.myu.umn.edu/jobs/ext/36547 6
- Reposted by Fabrice Jean-PierreNew lab paper! Andrew Frando describes how MexT alters the quorum sensing cascade in P. aeruginosa. /1 With Nicole Smalley; two undergraduates, Jamal Omar and Bobby Parsek; and @dezieleric.bsky.social, @mariecg.bsky.social, and Mylène Trottier at INRS in Montreal journals.asm.org/doi/10.1128/...
- Reposted by Fabrice Jean-PierreNew in JB: Black and Wakeman review the challenges of treating polymicrobial infections in various body sites, a topic near and dear to my heart. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
- Reposted by Fabrice Jean-PierreTwo tenure-track faculty positions open in our department: 1) Microbial Ecology and Evolution careers.rpi.edu/en-us/job/49... 2) Cellular Neuroscience careers.rpi.edu/en-us/job/49... Join our collaborative, interdisciplinary community, which has proved to be a fantastic place to start a lab!
- Reposted by Fabrice Jean-PierreThe abstract submission deadline for Microbes in Microbiomes has been extended to Wednesday, 26 November 2025 at 23:59 GMT. Submit now: microb.io/474FuXW%F0%9...
- Reposted by Fabrice Jean-PierrePls share: Secchi group at ETH Zürich is recruiting two fully funded, four-year PhD positions for an SNSF-funded project investigating the nonlinear rheology of bacterial biofilms. Deadline: 30 November 2025. Full advert and submission details: jobs.ethz.ch/job/view/JOP...
- Walking in the lab and seeing this = lots of data incoming! #microsky
- Reposted by Fabrice Jean-PierreNew tools unlock #Bdellovibrio bacteriovorus’s predatory secrets 🦠. By combining inducible gene expression with #CRISPRi-mediated depletion for precise control of essential genes, @lalouxlab.bsky.social uncovered new insights into its unique lifecycle and cell division. buff.ly/FcDzAY4
- “Pseudomonas aeruginosa-secreted respiratory toxin HQNO triggers fatty acid accumulation in respiring Staphylococcus aureus, decreasing SaeRS-dependent transcriptional regulation” #microsky journals.asm.org/doi/full/10....
- Extension de la date limite pour la soumission de résumés pour le BiSP2025/Micrhub au mercredi 15 octobre prochain à midi. Ne manquez pas ça ! @micrhub.bsky.social #microsky
- Pour soumettre, c’est par ici ✨👉🏻 event.fourwaves.com/bispmicrhubsherbrooke
- Reposted by Fabrice Jean-PierreAbstract submissions are closing! Submit your abstract for the Microbes in Microbiomes Miami 2026 meeting now! Submissions close Monday 20 October 2025 23:59 GMT. Apply today - microb.io/MiM26Abstracts #MiM26
