Discovery of an entirely new potential approach to atherosclerotic heart disease: targeted immunotherapy!
Studies in human coronary arteries to reduce plaque and the mouse experimental model. Another win for spatial multiomics
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www.science.org/doi/10.1126/...
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Vascular smooth muscle cell (VSMC) diversification drives atherosclerotic coronary artery disease (CAD). Mechanisms governing these cell state transitions remain unclear. We applied multiomic single-c...
