Anne Carpenter
Dedicated to drug discovery, enthralled by science. 5 kids. She. SAB Recursion. Founder SyzOnc. Lab at Broad Institute. Opinions my own.
- Reposted by Anne CarpenterNSF GRFP applicants (and mentors): Was your application Returned Without Review and deemed ineligible despite fitting in the allowed topics? 1) Write NSF 2) Write your Congressperson 3) CC us at grfp@grant-witness.us so we can compile + follow up Details and template at grant-witness.us/grfp-letter
- Reposted by Anne CarpenterLook I'm not going to open a cake decorating business any time soon but I think there's enough whimsy here for a 3-year old's birthday party
- Reposted by Anne CarpenterMy weekly update (Grants with Notice of Award dates up to 1/23/26) All projects 1/3
- Reposted by Anne Carpenter@bethcimini.bsky.social and I talk about the Cell Painting Assay a LOT, especially on our podcast Ask Erin/Dear Beth, so we figured it was about time to talk about what it actually is! youtu.be/9-d6DoHtgUY h/t @drannecarpenter.bsky.social #science #biology #cellpainting #microscopy #imageanalysis
- Reposted by Anne CarpenterEp 23 - So what actually IS CellPainting anyway? You may have heard of it if you're say, a fan of the @drannecarpenter.bsky.social - @shantanu-singh.cc lab (and who isn't????), but what, you know, is it? Let @erinweisbart.bsky.social break it down for you! youtu.be/9-d6DoHtgUY
- Ep 22 - while we all love CellProfiler (right??), we know that often the challenging part is handling the "bookkeeping" to get your data into it in the first place. @erinweisbart.bsky.social and I do a quick overview, and then point to great longer-form materials. Welcome to AE/DB 2026!
- Reposted by Anne CarpenterBefore the 1990s, plane crashes caused by microbursts used to kill planeloads of people fairly regularly. Dr. Ted Fujita and NCAR scientists figured out how to detect microbursts and warn pilots about them. Since then? Zero airliner crashes from microbursts.
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In addition, the genetic contribution has remained stable over time, which also means that the much smaller contribution of environmental factors has also remained stable. Therefore environmental factors are unlikely to explain the increase in the prevalence of ASD. pubmed.ncbi.nlm.nih.gov/32374377/ - Reposted by Anne Carpenter"If he had so little ability to distance himself from Jeffrey Epstein even after all that was publicly known about Epstein's sex offenses involving underage girls, then Summers cannot… teach a generation of students at Harvard or anywhere else." - @warren.senate.gov www.cnn.com/2025/11/17/p...
- Reposted by Anne CarpenterI did it again. @globias.bsky.social #GloBIAS2025 Here's hoping I get a chance again next year.
- If you give an image of image analysts to an image analyst, you better believe I'm going to analyse it. #GloBIAS2024 What a great meeting.
- Reposted by Anne CarpenterA senior academic using mentoring as leverage to obtain sex is a contemptible abuser of power.
- Summers conferred with Epstein frequently about how to extract sexual favors from a Harvard econ grad (AB '04, PhD '09) The grad is from China Epstein and Summers referred to her by the codename "Peril" Racism and sexual exploitation in one efficient package bit.ly/3LHpin8
- Reposted by Anne CarpenterThis is what I try to always tell people: food banks can do way more with your money than you can, due to bulk buying deals. And they can do way, way more with your money than with the canned goods you didn’t want to eat
- Reposted by Anne CarpenterBiologist David Sabatini loses again in legal fight against Whitehead Institute | Science | AAAS www.science.org/content/arti...
- Required reading for cell biologists to get a sense of basic statistical principles! www.nature.com/articles/s41...
- Reposted by Anne Carpenter[This post could not be retrieved]
- Reposted by Anne CarpenterIt’s Halloween so time to make the cells scream!
- Reposted by Anne CarpenterThere's a year-old problem with looping movies in Powerpoint on Mac. Movie plays once, jitters and then shows blocky artefacts. Same pptx works fine on Windows. Problem seems to be Mac-side (QT?) but 15.7.1 and 26.0.1 both show this behaviour. A solution, in case it helps anyone: 1/2
- Reposted by Anne Carpenter💡Just presented our new paper at the @iccv.bsky.social BioImage Computing workshop: cubic: CUDA-accelerated 3D Bioimage Computing. We introduce a simple way to add GPU acceleration to scikit-image–based bioimage processing pipelines by swapping import statements. 🧵 1/6 #iccv2025
- Reposted by Anne CarpenterThe editors of ACS Omega cheerfully accepted the authors' excuses and replacement image for this weird shit. pubs.acs.org/doi/10.1021/... H/t Leonid @forbetterscience.bsky.social
- Reposted by Anne Carpenter"Here we show that heartbeat sound promotes structural and functional maturation of human cortical organoids with a physiological astrocyte-to-neuron ratio." 🤯 www.biorxiv.org/content/10.1...
- Free webinar, looks good (wish it wasn't scheduled during Day 3 of SBI2 conference in Boston!) webinars.liebertpub.com/e/The-State-...
- Reposted by Anne CarpenterPresident Trump reduces trade surplus in profitable export industry that provides middle-class jobs all across America.
- Reposted by Anne CarpenterDartmouth is OUT! Thank goodness... a friend at U of A and I have been playing "Who will be the last of the 9 standing?" and it's not gonna be us!
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- Reposted by Anne CarpenterBig news! Our week-long #bioimageanalysis bootcamp is BACK! Learn how to think about bioimage analysis like the pros do, learn what corrections you should (and shouldn't!) apply to your images, learn open source tools, and more. Apply NOW at broad.io/BAB3 for our January 2026 course!
- Reposted by Anne Carpenter[This post could not be retrieved]
- Reposted by Anne CarpenterPeople often dismiss cell biology as just “looking at stuff”, which makes seminal discoveries like this even sweeter. Congrats @drannecarpenter.bsky.social and team
- 15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵
- … unless you’ve heard me talk about it, which I’ve done a lot over the past decade :D Including in this Quanta video: youtu.be/KDQFUmDJ3nY?... But now this project is finally preprinted!! The answer is skin cells. Skin cells! www.biorxiv.org/content/10.1...
- That seems really odd, but lots of cells share lots of components and processes that are used in different ways in different cell types. And not-fun fact: psychotic symptoms are associated with skin abnormalities.
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View full threadThanks to the funders who believed in us, enabling us to complete this work in pieces over time: NIH NIGMS, Merkin Institute, BroadIgnite, BBRF, Harvard-MIT Neurodiscovery program, and the Program for Neuropsychiatric Research at McLean Hospital.
- Reposted by Anne CarpenterThe recording of "Illuminate variant impact with images" by @drannecarpenter.bsky.social and Runxi Shen is now available: youtu.be/l8y00jKXJx4 This talk is part of @broadinstitute's MPG Primer series. For more info, check out broad.io/MPGPrimer
- Reposted by Anne CarpenterIn Somebody’s Daughter, I wrote about a middle school teacher who was super kind to me, and how he influenced me to expand on my preoccupation with reading by encouraging me to write as well. Earlier today, at the Indiana State Library, his adult daughter was in my nonfiction writing workshop 🥹
- Reposted by Anne CarpenterAgain: if you are attending a meeting and start coughing or sneezing in response to an oncoming cold, excuse yourself. Or at least wear a damned mask. Respect your colleagues.
- Reposted by Anne CarpenterBREAKING: A federal judge has ordered Trump to restore $500 million in frozen UCLA NIH grants. The same judge, Rita F. Lin, previously ordered all UCLA NSF grants reinstated. Lin has now nearly entirely reversed Trump's July de-funding of UCLA research: www.latimes.com/california/s...
- Reposted by Anne CarpenterThe word “autism” was first used to describe behavioral differences in children in 1911 but autism has been documented using available records going back to the 1700s (definitively) and further. Acetaminophen (Tylenol, paracetamol) was discovered in 1878 and first sold in the United States in 1950.
- Reposted by Anne CarpenterHere's the link if u want 2 attend the AI & Data Sci panel on Fri 9/19 w/speakers incl Enoch Huang, @drannecarpenter.bsky.social Jeremy Jenkins, Enrique Garcia-Rivera. Listed after the keynote by Vertex SVP Mark Bunnage thebiotechclub.org/career-fair cc Boston Protein Design Club & @sokrypton.org
- Reposted by Anne CarpenterPfizer's VP Machine Learning Enoch Huang, the Broad Institute's @drannecarpenter.bsky.social Novartis VP Jeremy Jenkins, Formation Bio's Head of Data Science Enrique Garcia-Rivera & Vertex alum Maria E. Morales are speakers on 9/19 AI & Data Sci panel at @harvardmed.bsky.social. Link is ⬇️ #biosky
- Reposted by Anne CarpenterI want to start a new global movement: Meetless Monday - we encourages people to reduce their meeting activity by one day each week for personal health and the planet's well-being.
- Reposted by Anne CarpenterAfter careful consideration of the current situation and the tools at our disposal at this present time, I have made the strategic decision to Lie Down For a Bit
- Reposted by Anne Carpenterprincipal investigator component analysis
- Reposted by Anne CarpenterMore foundations should do this: "Funding is exclusively available to applicants who have already received federal funding (e.g., from the NIH, CDC, NSF) for their health equity research, but have since had their funding rescinded due to federal administrative actions" www.rwjf.org/en/grants/ac...
- Reposted by Anne CarpenterHappy upcoming Pioneer Award Application Day to all who celebrate. I was mentioning that the best review comment I've ever gotten came from the related DP2 (New Innovator) mechanism. Enjoy this throwback to #GrantReviewGreatstHits as the deadline gets closer! May you all do better than I've done!
- Reposted by Anne CarpenterJOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!
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- Reposted by Anne CarpenterAs an anthropologist, I'm inclined to try to understand stuff that looks like magical thinking rather than mock it, but proposing to build a God and then expecting him to tell you how to get rich is really testing all of my professional training...
- Reposted by Anne CarpenterIt is impossible to explain to civilians how it feels to finally, FINALLY, land a clearly within-payline NIH grant score and then have it go unfunded because of all this regime bullshit. You all have my sympathies. Unfair doesn’t even begin to describe it.
- Reposted by Anne CarpenterThe order to restore grants applies to 300 NSF grants, not the NIH grant suspensions
- Reposted by Anne CarpenterYou can tell the world has gone to shit because last time I was at the dentist the hygienist asked me if I was regularly flossing and I said that I only do it sometimes and she was like yeah that’s fine I don’t really care
- Reposted by Anne CarpenterIt’s just matrix multiplication
- Reposted by Anne Carpenter$200 million from Columbia $500 million from Harvard $1 BILLION from UCLA?!
- Reposted by Anne CarpenterOh so it does have phd level intelligence
- Reposted by Anne CarpenterA paper from the JUMP Cell Painting Consortium presents image-based phenotypic profiles for 75% of the protein coding genome of human U-2 OS cells, offering a valuable resource for exploring gene relationships. @shantanu-singh.cc @drannecarpenter.bsky.social www.nature.com/articles/s41...
- Reposted by Anne CarpenterMorph Map is now published in Nature Methods. Excited to see what the community discovers with this resource mapping ~15,000 human genes! rdcu.be/ezGre
- Now on biorxiv! The JUMP-Cell Painting Consortium’s paper: “Morphological map of under- and over-expression of genes in human cells” This is the genetic perturbation portion of the JUMP’s dataset; our chemical perturbation paper will come in a few months www.biorxiv.org/content/10.1...
- Reposted by Anne CarpenterCheck out this opportunity to join my lab as a postdoc! www.ebi.ac.uk/research/pos... Every year, faculty from EMBL-EBI and the Wellcome Sanger Institute co-develop projects that allow fellows to be part of ✨both✨ of these amazing research institutes.
