Thaís Dal’Sasso
Computational and systems biology 👩🏻💻, adaptive evolution 🧬, plant-microbe interactions 🪴 | Postdoc @envgenlab.bsky.social
- Congrats @marco-guerreiro.bsky.social. @estukenbrock.bsky.social and colleagues on this exciting study linking codon optimization and adaptive translation to lifestyle transitions in a group of fungi.
- Emerging fungal pathogens have detrimental impacts on crops, animals, and humans. This study demonstrates that the fungal transition from saprotroph to opportunistic human pathogen is likely facilitated by adaptive translation. www.nature.com/articles/s41...
- Reposted by Thaís Dal’SassoThe scikit-bio paper in online in Nature Methods! Many thanks to our collaborators, community contributors and reviewers! We couldn’t have done it without you. www.nature.com/articles/s41... #Bioinformatics #OpenSource
- Reposted by Thaís Dal’SassoWishing you all happy holidays. 🎄🎁 Greetings from the Environmental Genomics Group. 🇲🇽🇫🇷🇧🇷🇵🇹🇵🇪🇷🇸🇮🇷🇩🇰🇩🇪🤗
- 🎉 Our new paper is out! We assembled a telomere-to-telomere genome 🧬 of Sporisorium scitamineum and showed how two smut strains with contrasting virulence deploy distinct early-infection programs on resistant and susceptible sugarcane genotypes. DOI: doi.org/10.1186/s128...
- Personally, I’m very happy and proud to have contributed to this work during my postdoc at the University of São Paulo. Huge congratulations to Pedro Vilanova on his first first-author paper, and to our amazing PI Prof. Claudia Monteiro-Vitorello! 👏 #MPMI #FungalGenomics #Transcriptomics
- Had a great time organizing & teaching the MadFungi transcriptomics workshop. We spent three amazing days on RNA-seq for plant–microbe interactions and had great conversations with brilliant MSc/PhD students! 🌱🍄 #RNAseq #PlantMicrobeInteractions #Bioinformatics #PlantPathology
- Reposted by Thaís Dal’SassoImportant read if you use LLMs for science knowledge discovery around plants "What Large Language Models Know About Plant Molecular Biology" www.biorxiv.org/content/10.1.... As per usual LLMs appear to propagate biases.
- Reposted by Thaís Dal’SassoReally happy this is out in preprint - Congratulations to @graemekettles.bsky.social @zymohaider.bsky.social, and everyone involved for their hard work completing this study! It examines a Z. tritici effector that is a molecular mimic of plant LRRs, and suppresses PTI www.biorxiv.org/content/10.1...
- Reposted by Thaís Dal’SassoDolly (@dollymehta.bsky.social) developed a pipeline to screen for conserved #RNA structures across genomes. She then applied it ~14,000 #plastid genomes and identified nearly 60 conserved structures. doi.org/10.1101/2025...
- Great talk this afternoon by Joy Bergelson at #ESEB2025! 🌱 She showed how a small number of NLRs in Arabidopsis can recognize P. syringae, and how a protein interaction model can help explain ETI responses.
- Reposted by Thaís Dal’Sasso📣 Happy to see the journal publication 📄 of our work on Starships 🚀 in Verticillium fungi: terrific work led by @yukiyosato.bsky.social rdcu.be/exBSp
- Reposted by Thaís Dal’SassoIn #GENETICS, @3rdreviewer.bsky.social and @smishra677.bsky.social show it is possible to estimate recombination solely using the allele frequency spectrum and provide a genealogical interpretation of the results, showing how #MachineLearning can provide insights into biology. buff.ly/emixz9W
- Reposted by Thaís Dal’Sasso#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible! Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵 www.biorxiv.org/content/10.1...
- Reposted by Thaís Dal’SassoNew online! A genomic perspective on fungal diversity and evolution
- Admixture’s impact on Brazilian population evolution and health | Science www.science.org/doi/10.1126/...