Andreas Walther
Professor in Mainz/GER for Life-Like Systems and Materials, Max Planck Fellow, Travel and Food Enthusiast 🧳, AvHumboldt Postdoc-Scout 📧 me
https://www.walther-group.com
- 🧪🧠 New preprint out! Soft Hardware, Flowing Software We introduce reconfigurable microfluidics as an active control layer for chemical computation. Geometry, and flow, and not molecular redesign, programs function. Great work by Piet! chemrxiv.org/doi/full/10....
- 💡 The core idea: Instead of encoding computation only in chemistry, we make the reaction vessel itself programmable. Soft hydrogel structures can be written & erased in situ, reshaping flow, mixing, and reaction environments on demand. #3Dprinting #microfluidics
- 🔁 This enables something powerful: The same molecular system can perform different computations simply by changing physical structure. No new DNA strands. No new chemistry. Just new geometry. #chemicalcomputation #systemschemistry
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View full thread🔮 Why this matters: Reconfigurable soft microfluidics point toward adaptive chemical matter, embodied computation, and future closed-loop chemical learning systems. #physicalintelligence #softmatter #adaptivematerials
- I will soon be in Singapore (22-31.Jan) for the Dean's Distinguished Speaker Series #NTU #Singapore hosted by Ali Miserez. Very excited to go and thank you to Ali! @Singaporean researchers, if you want to meet me, I am happy to do so. PLease send me a direct message.
- Schrödinger was in our canteen and the decision is yet to be made. 🤯😳at least 50 % chance to get it right.
- Reposted by Andreas WaltherMultidisciplinary training, over time, produces the highest impact people www.science.org/doi/10.1126/...
- Fun Xmas day with a team of amazing people. Life is good 😊
- Taking my @sfb1551.bsky.social socks for another spin to visit Silvia Vignolini at the MPI in golm. A long trip…
- Let’s get the show on the road. Best way to start the day. #roma
- I made it to Cambridge 😀. Looking forward to meeting some ECRs and speaking later today at the Engineering Biology Forum.
- Duck 🦆 - chestnuts 🌰 - carrot 🥕- blueberrry 🫐 #chemistswhocook
- Saturday 🧑🍳. Cod loin, cauliflower coconut purée, cilantro/lime oil and some barberries.. #chemistswhocook #silkysmoothpuree
- Looking very much forward to speaking at the Institute for Molecules and Materials in Nijmegen tmrw. Deutsche Bahn is playing all tricks to prevent me from reaching it.

- Congratulations to Soumya and Charu for making the first ATP-fueled homeostatic cytokine delivery system for communication between artificial and living cells. Now in Angewandte Chemie @angewandtechemie.bsky.social #syntheticcell #noneqsys #DNAnanoscience onlinelibrary.wiley.com/doi/10.1002/...
- Fresh in @natchemeng.nature.com Growing artificial cytoskeleton in the viscoelastic confinement of DNA Artificial Cells. Brilliant work bey Weixiang! #Syntheticcell #systemschemistry www.nature.com/articles/s44...
- Reposted by Andreas WaltherJoin us at our EngBio Forum on 10 Nov to hear from Andreas Walther @waltherlab.bsky.social on creating programmable materials and DNA-based synthetic cells that can process information, adapt,and communicate. Don't miss it! Sign up 🫱 buytickets.at/engineeringb... #SyntheticCells #LifeLikeSystems
- Reposted by Andreas Walther🖥️ New Publication Alert Congratulations to Eric Schumbera, @dormannlab.bsky.social, @waltherlab.bsky.social & @miguelandrade66.bsky.social on their recent publication in BMC Genomics #RGmotifs #IDRs #LLPS #HumanProteome #ComputationalMotifAnalysis bmcgenomics.biomedcentral.com/articles/10....
- Reposted by Andreas WaltherWe're extremely excited to welcome Prof Andreas Walther @waltherlab.bsky.social and Dr Claudia Contini @continiclau.bsky.social for our next Forum We'll be exploring #SyntheticCells #LifeLikeSystems and #EngineeringBiology from the bottom-up Don't miss it, register now! 👉 bit.ly/engbio-forum-nov25
- Reposted by Andreas WaltherReally happy to see our most recent Voices article, on the importance of DEI in science, published this week. Includes perspectives from 8 researchers from the USA, UK, China, and Bangladesh www.cell.com/cell-reports...
- 🚨Oli's soft robotic engines are now in #AdvancedMaterials. A new paradigm for hydrogel actuators - non-reciprocal motion. Kinetic asymmetry rocks advanced.onlinelibrary.wiley.com/doi/full/10.... #softrobotics #ercfunded @erc.europa.eu #hydrogel #actuator #noneqsys #lifelike #physicalintelligence
- 🚨Miao's and Weixiang's work on RNA transcription in DNA based condensates as nucleus mimics is now out in @natcomms.nature.com www.nature.com/articles/s41... #syncell #DNA #condensate #LLPS. Great work to understand transcription and LLPS in #crowded #viscoelastic environments @sfb1551.bsky.social
- 📄🚨 Great work by @Lorena now out in @jacs.acspublications.org "DNA Flipping as Facile Mechanism for Transmembrane Signaling in Synthetic Cells" We show that simple chol-ssDNA does not stay on the outside of GUV membranes but flips inside and can trigger reactions. pubs.acs.org/doi/10.1021/...
- What a surprise, we always think that chol-ssDNA stays on the outside of the membrane, but here we learn that this is not correct! Generic across many lipid compositions, for different DNAs. Everything flips! A defect-mediated process. #syncell #DNAnanoscience #RNA A great information highway!
- A few great days in Vienna at the #schroedinger Institut for a Workshop on #softmatter. Wonderful to meet old Friends from our EU ITN polyamphi from my PHD times. Check out the toilets in the Institute 🫨.
- We have a new Dr Zixuan in Tampere !! Congratulations and thank you for the discussion.
- We have a new Dr Zixuan in Tampere !! Congratulations and thank you for the discussion.
- Heading out to Tampere for a PhD Defense with @arri-priimagi.bsky.social . Looking forward to some good discussions. 🇫🇮🇫🇮🇫🇮
- Tomahawk vs chateaubriand. Chateaubriand wins. What a lovely dinner with friends. #chemistswhocook.
- I think #linkedin has entered a new age, where AI and LLM are sending it into self-amplifying cycles of praise and gratitude till explosion of data centers. 😆😆

- Reposted by Andreas WaltherATP-Powered Signaling between Synthetic and Living Cells biorxiv.org/content/10.1101/202…
- Become my colleague!!! We are recruiting in a junior faculty level. Junior Professor for Theoretical Chemistry of Macromolecular and Supramolecular Systems #simulations #theory #noneqsys #assistantprofessor #chemjob Thank you for sharing this. berufungsportal.uni-mainz.de/ausschreibun...
- A new Tool has arrived in our lab: 2 Photon Lithography by #upnano. Now we can print across all scales. Funded through the @carlzeissstiftung.bsky.social putting it to work for neuroregeneration. #biomaterials #3Dprinting
- Fantastic group excursion with the #team. Down the Rhine valley. Great weather, great team, great fun. And huge schnitzel in the evening. Absolutely loved the day.
- Adjusting a pool with the very generic pH + and pH - chemicals. Putting my entire academic skillset to work!
- Reposted by Andreas Walther@waltherlab.bsky.social taking us on a magical ride about adaptive soft matter. What a treat and fantastic talk at @uniulm.bsky.social!
- Small tour in Ulm; looking froward to my @gdch.de lecture today. Most special hotel built in 1300. “The tilted hotel”
- #chemistswhocook Merisier cherries for the duck. - handpicked by myself - because you cannot buy them. So good.
- ACDC PwrUp tour. It’s amazing to see the old giants in action.
- Great recognition for Joshua Krehan's work on Homeostatic Artificial Cells (in Chem) by colleagues from China, who wrote a two-page highlight about our work (www.sciencedirect.com/science/arti...).
- Thank you very much for this thoughtful piece of work! Our original article remains a featured article on the Chem website. I am happy it receives this type of recognition, because I am equally excited about it. It opens doors to very complex life-inspired behavior. www.cell.com/chem/fulltex...
- It’s been a while since I contributed to #chemistswhocook. Tomahawk 🇺🇸 vegetable tian 🇫🇷 and mozzarella di bufala 🇮🇹. Delicious 😋
- This needs wider attention 🥳.
- The bony-eared assfish has the smallest known brain-body mass ratio of all vertebrates ... well, it has to be someone 😆 en.wikipedia.org/wiki/Brain%E...
- Well done Hungary! #Diversity is strength.
- Reposted by Andreas WaltherIn my recent News & Views in @natnano.nature.com I highlight a new exciting work by @waltherlab.bsky.social on programmable ballistic wave diffusion in DNA #condensates
- 🚨 Two weeks left to apply for our joint #PhD position with @landfesterdept.bsky.social. “Ultraspecific mRNA delivery for targeted neurotherapeutics”. More details 👇🏼
- 🚨🚨Together w/ @landfesterdept.bsky.social from @mpip-mainz.mpg.de, we are recruiting a joint #PHD #researcher on the topic of "Ultrapecise mRNA Delivery for Targeted Neurotherapeutics" in a larger collaborative center. #phdposition #chemistry #biomedicalengineering #mRNA #syntheticbiology RT = 😍
- Some final impressions from the #erc grantees chemistry conference in Porvoo. Thanks so much to @arri-priimagi.bsky.social and Olli Ikkala for organizing this great event!
- Just checked in in Porvoo for the 6th #ERC grantees conference. Finland always brings back great memories to my postdoc time @erc.europa.eu