Kara Margolis
Pediatric gastroenterologist and physician scientist; Director of the NYU Pain Research Center; gut-brain enthusiast, especially when it comes to mood and neurobehavior.
- Happy holidays from the Margolis lab! Pic after a hard core karaoke party😂
- Reposted by Kara MargolisShoutouts to @nyupainresearch.bsky.social @vabraira.bsky.social @dr-lupo.bsky.social @sdavidson.bsky.social @karapedsgastrodoc.bsky.social for helping organize!
- Excited to announce the first NYC Area Pain meetup being hosted at NYU. Come connect with other pain researchers and learn about the advances being made by early career researchers. RSVP: luma.com/m5zwchlt?tk=... Still accepting submissions for lightening talks, reach out if interested.
- Reposted by Kara MargolisNew research reveals that the gut can sense microbial flagellin via TLR5-expressing neuropod cells, triggering PYY release & reducing feeding through a gut–brain neural circuit—independent of microbiota or immune cues. @karapedsgastrodoc.bsky.social 🔗 www.nature.com/articles/s41...
- @chalysthalee.bsky.social did an amazing job presenting at the ISSR! Such a well-deserved travel award and so proud to have her representing the lab!!
- Just back from a great week in Vienna for #ISSR2025. I am grateful for the travel award and the opportunity to share my work. Big thanks to @karapedsgastrodoc.bsky.social and Mike Gershon for their steady support in the lab and my career. Loved connecting with 5-HT researchers from around the world!
- Reposted by Kara MargolisA new study shows that food structure plays a key role in determining which gut hormones are released. @karapedsgastrodoc.bsky.social #GLP1 #GutBrainAxis #FoodStructure #Type2Diabetes #ImperialCollege 📖 Nature Metabolism www.nature.com/articles/s42...
- Reposted by Kara Margolis🩸 A new blood test (WBAIL-2) detects gluten-triggered IL-2 release, offering a non-invasive, accurate way to diagnose celiac disease, even in patients on a gluten-free diet! 🌾❌ Game-changer for gut health. sciencedirect.com/science/arti... #guthealthmatters #WBAIL2 @karapedsgastrodoc.bsky.social
- Reposted by Kara MargolisExcited to share my first senior author paper in Pain! 🎉 We identify Synaptojanin 1 & Endophilin A1 as key endocytic mediators of nociception. Silencing them blocks spinal synaptic transmission and relieves pain in cancer & postoperative models, without affecting normal behavior. buff.ly/caKMGY3
- Reposted by Kara MargolisHow bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)
- Reposted by Kara Margolis🎤 BLINK AND YOU'LL MISS IT: FLASH TALKS AT THE 5TH ANNUAL AMPIRS! ⚡ This year’s Flash Talks were a whirlwind of brilliance 🎤one mic, infinite insight. And WOW, did our presenters deliver! 👏PRC representing! #PRCpride #violetpride #NYUDental #nyuniversity
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- Reposted by Kara MargolisNew study! Aging and nerve injury cause senescent neurons in the peripheral nervous system, driving increased pain; targeting these cells could offer a new pain treatment especially in older adults. @vivtawfik-mdphd.bsky.social @karapedsgastrodoc.bsky.social www.nature.com/articles/s41...
- Reposted by Kara MargolisIL-18 signaling in epithelial-derived enterochromaffin cells plays a pivotal role in injury response and stem cell activation in the mouse intestine #gutresearch #epithelialcells #IL18 #stemcells @karapedsgastrodoc.bsky.social www.pnas.org/doi/10.1073/...
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- Reposted by Kara Margolis🚨Sound the alarm- it’s an AMPIRS photo dump! 🚨Poster Session 1 brought the heat 🔥 Big shoutout to our amazing PRC members who rocked their posters! #NYUDental #nyuniversity #AMPIRS #Painresearchcenter
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- Reposted by Kara Margolis💡 A promising non-opioid strategy—SBI-810 reduces pain, opioid reward, withdrawal, and constipation through selective β-arrestin-2 signaling www.sciencedirect.com/science/arti...
- Reposted by Kara MargolisA big shoutout to Nikhil Sharma for joining our MPB Seminar Series! 🙌 @nyupainresearch.bsky.social loved your fascinating deep dive into the enteric nervous system and its connection with peripheral sensory & autonomic ganglia. 👨🔬🧠✨ #Neuroscience #PainResearch #MPBSeminar
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- Reposted by Kara MargolisPRC Highlight: Welcome to the PRC-Structural Biologist Dr. Halil Aydin and Dr. Nestor Jimenez-our Director of the PRC e-phys core!! We are so excited to have you join the team! 👏🥳🎉
- Incredibly excited to work with our new neighbors in the Hi bell lab!!
- Wonderful talk on immuno-modulatory materials from Jeff Hubbell, NYU’s new Vice President of Life Sciences and Engineering. We are excited to welcome the Hubbell Lab as our new neighbors!🧠💥🌟 @nyupainresearch.bsky.social @nyutandon.bsky.social @karapedsgastrodoc.bsky.social
- Fantastic science and even more fantastic colleagues @amergastroassn.bsky.social this week. Excited and honored to be elected vice chair of the neurogastro council and work with @brad kuo and Council members! @nyupainresearch.bsky.social @newyorkuniversity.bsky.social @nyulangonepccsm.bsky.social
- Reposted by Kara Margolis🎉 Congrats to @sarahanajjar.bsky.social on her awesome Data Blitz presentation and poster, “Sex Differences in Gut Serotonergic Signaling of Visceral Pain” at the USASP meeting in Chicago! 🧠💥🌟 @karapedsgastrodoc.bsky.social @nyupainresearch.bsky.social @usasp.bsky.social
- Reposted by Kara MargolisWonderful talk on immuno-modulatory materials from Jeff Hubbell, NYU’s new Vice President of Life Sciences and Engineering. We are excited to welcome the Hubbell Lab as our new neighbors!🧠💥🌟 @nyupainresearch.bsky.social @nyutandon.bsky.social @karapedsgastrodoc.bsky.social
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- Amazing times with @nyupainresearch.bsky.social at the @usasp.bsky.social meeting. Congratulations to all our post docs including @pazduran.bsky.social @sarahanajjar.bsky.social for their amazing presentations! @nyupainresearch.bsky.social @newyorkuniversity.bsky.social
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- Reposted by Kara MargolisPRC Highlight: The Jensen Lab is making strides in understanding diseases at the molecular level — paving the way for #future breakthroughs in #oral health and beyond #NYUDentistry #nyuniversity #Jensenlab #3minutemondays
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- Reposted by Kara MargolisPRC Highlight: @nyupainresearch.bsky.social Dr. Steve Davidson was featured in The New York Times- offering his insights on a BMJ review that examined studies on non-surgical, interventional treatments for low back pain nytimes.com/2025/03/18/w... #nyuniversity #NYUDental #NinaAgrawal @nytimes.com
- Reposted by Kara MargolisCONGRATULATIONS to Drs. Sarah Najjar, Lin Hung and Kara Margolis- Their review article: Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation is one of the top 10 most cited articles published in 2023! onlinelibrary.wiley.com/doi/abs/10.100… 🥳🔝🔟
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- Reposted by Kara Margolis#itchdoctor Exciting study from the Kim Lab on how mast cells and sensory neurons drive cross-organ pain 💥🧠 #VisceralPain #NeuroImmune #IBS #ICBPS www.researchsquare.com/article/rs-6...
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- Reposted by Kara MargolisFascinating new article from the Basbaum Lab! Elora Midavaine et al. show that regulatory T cells can curb pain via endogenous opioid signaling - but only in female mice. #PainResearch #Neuroimmunology #Tregs #SexDifferences #Enkephalin www.science.org/doi/10.1126/...
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