did:plc:vnukq35miprmqpgqmphnu7a4
Emmy Noether Research Group Leader,
Professor for Molecular Pathology in Neuro-Oncology, Neuropathologist at University Hospital Hamburg-Eppendorf
Research Interests: Proteomics, DNA-methylomics, Bioinformatics, Preclinical Models,
Digital Pathology
- **** Cumulative Copy Number Variation Analyses based on DNA methylation data **** We present our new tool CCNV - now out in BMC Bioinformatics! link.springer.com/article/10.1...
- ** High performance #dataintegration for large-scale analyses of incomplete Omic profiles ** Meet BERT (our new algorithm Batch-Effect Reduction Trees) - details in #naturecommunications : www.nature.com/articles/s41... #transcriptomics #proteomics #metabolomics #dataanalysis #zmnh #ukeHamburg
- I** Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes ** Now out in Acta Neuropathol Commun: actaneurocomms.biomedcentral.com/articles/10.... Special thanks to the Roggenbuck Foundation for funding! #Neurooncology #Neuropathology #zmnh #ukeHamburg
- Jelenas work on #spatialproteomics of the developing brain has now been published in Molecular md Cellular Proteomics (www.mcponline.org/article/S153... ) #neurooncology #neurodevelopment #proteomics #Neuropathology #zmnh #ukeHamburg
- ***News on Neurocytoma*** Read about outcome-associated factors in a molecularly defined cohort of central neurocytoma in Acta Neuropathologica: link.springer.com/article/10.1... Happy to have contributed to the study! #neurooncology #Neuropathology #braintumor
- Antonia Gocke representing our group at #SNOPeds2025 ! She shows our data on LIN28A in atypical teratoid rhabdoid tumors and proteome data on a large cohort of #ependymoma. Fantastic job Antonia! #atrt #braintumor #pediatriccancer #kinderkrebs #proteomics #neurooncology #Neuropathology #zmnh
- Dear Jelena, now you successfully defended your PhD ‐ congratulations! We are very happy to have you in the team! #proteomics #etmr #spatialproteomics #zmnh #ukeHamburg #neurooncology #neurodevelopment #neuropathology
- Ever wondered how different biological datasets can be combined in the best way (e.g. data from #transcriptomics #proteomics #DNAmethylomics)? Have a look at our #review paper describing challenges of #data integration and available #algorithms and tools. doi.org/10.1002/pmic...
- ***Update on efficient data integration*** We provide significant improvements to the #HarmonizR approach: 1) Improved runtime 2) Retainment of more features (feature rescue of up to 103.9% for tested datasets) link.springer.com/article/10.1... #transcriptomics #proteomics #bioinformatics
