- We are pleased to highlight this article published by @gruberlab.bsky.social. At DCI, F. Roisne Hamelin and collaborators used electron microscopy — and in particular our streptavidin affinity grids — to reveal the mechanism by which Wadjet binds to the plasmid to initiate loop extrusion.
- How do SMC complexes load onto DNA to get ready for loop extrusion? @roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸♂️🤸♂️🤸♂️. Check out the new paper: www.cell.com/molecular-ce...
