Levental Lab
laboratory on structure and functions of living membranes lab at University of Virginia ; also posts occasional nonsense - views our own, not UVA
www.levental-lab.com
- Reposted by Levental LabAn intracellular meteor shower. EB3 comets tracking growing microtubule plus-ends in a cultured cell.
- Reposted by Levental LabLove every moment
- Reposted by Levental LabAI CEOs: "We will cure cancer in a decade." Media: "Wow, yay!" Actual cancer researcher and clinician: "Cancer's end is not conceivable." observer.co.uk/culture/inte...
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- Reposted by Levental LabToday at 17:00 CET - the first #MembraneTrafficking seminar of 2026. Giovanni D’Angelo (EPFL) and Sean Munro (MRC-LMB), explore protein trafficking, retention, and sorting at the Golgi. Join us for exciting discussions about the best organelle! Details at felixcampelo.wixsite.com/membranetraf...
- Reposted by Levental LabJoin us this Thursday (Jan 29) at 5pm CET for the first #MembraneTrafficking seminars of 2026, featuring two outstanding scientists, Giovanni D'Angelo (EPFL) and Sean Munro (@cellbiol-mrclmb.bsky.social), and the shared topic of protein trafficking, retention & sorting at the #Golgi 🥞
- Excited to share a new story that transformed how we think about membrane domains in the ER! rdcu.be/eR7Cn ER exit sites mediated by the COPII adaptor sec24D selectively recruit lipid raft-preferencing proteins for rapid ER export Wondering what’s so new and exciting? Skytorial below! 1/9
- 1. determinants of cellular location for many proteins are unknown 2. lipid rafts are implicated in post-Golgi traffic, but not early secretory (ER) 3. cholesterol, critical for lipid rafts, is low in ER 4. adaptors that help cargo exit ER (sec24) have four isoforms, some prefer raft proteins 2/9
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- Reposted by Levental LabI’ll soon share a call for a postdoc at Institut Jacques Monod (Paris) on fundamental mechanisms of membrane traffic and protein/collagen secretion in health and disease. Please get in touch if interested.
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- Reposted by Levental LabLLOMe has long been used to study lysosomal damage, yet how it works has remained a mystery. Using cryo-electron tomography, we show it forms amyloid structures inside lysosomes that mechanically rupture membranes – revealing a new paradigm for lysosomal failure. 🔗 doi.org/10.64898/202... #CryoET
- Reposted by Levental Lab10/10. No notes.
- Reposted by Levental LabThis shot from NFL Films is unbelievable
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- Reposted by Levental LabA greeting card for my Bluesky friends
- Reposted by Levental LabPosting this to X, Threads, and Bluesky as an experiment
- Reposted by Levental Lab⚠️ New pre-print just dropped! www.biorxiv.org/content/10.6... Bump-and-hole engineering has served us exquisitely to develop chemical tools that are specific for individual glycosyltransferases. Now, Yu Liu, Saskia Pieters and lots of colleagues have taken the method a step further!
- Reposted by Levental LabModern lipid biology has grown far beyond its roots. Advanced technologies offer novel opportunities to unravel the role of lipids in the organization of biological systems. Build on this momentum and join The EMBO Workshop "The Lipid Code to Life" Sept 7-11, 2026 meetings.embo.org/event/26-lip...
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- Reposted by Levental LabExciting preprint from @franbottanelli.bsky.social and @annespang.bsky.social! ARF-1 regulates FERARI-mediated endosomal kiss-and-run recycling by controlling selective cargo loading into vesicles. ARF-1 Coordinates Cargo Sorting at FERARI Endosomal Recycling Hubs www.biorxiv.org/content/10.6...
- Reposted by Levental LabHappy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7) www.biorxiv.org/content/10.6...
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- Reposted by Levental LabIt's the 3rd of January 1939, your name is professor James Smith and you are staring at a drawing of a fish. It's not a regular fish. It is a completely impossible fish.
- Reposted by Levental LabMagnificent. Make sure you click on the "1 more reply" link to make sure you read the whole thread. You will not regret it.
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- Great study and a nicely succinct explanation below!
- Thrilled to share our latest study, led by @reikatei.bsky.social, in @natchembio.nature.com! We began by asking a simple question—how do cells know if they have too much of a lipid in a particular membrane, and how do they respond to rectify this imbalance? www.nature.com/articles/s41... More info 👇
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- Reposted by Levental LabYeesh I hate being repetitive, and yet... It's time once again to remind my fellow Americans that there is no mechanism whereby state run elections can be suspended or canceled by the federal government. None. So don't go along with any garbage you hear to that effect. Laugh, and get ready to vote.
- Membrane asymmetry as promising anti fungal target!! Cool!! #lipidtime
- Reposted by Levental LabPapers submitted on Tuesdays are more likely to be accepted by Nature whereas Wednesdays seem the most likely day to submit and secure acceptance to PLOS ONE. For Cell, Mondays and Tuesdays seem the best submission days in case of accepted papers. link.springer.com/article/10.1...
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- Reposted by Levental LabHappy new year! I've so enjoyed the end-of-year lists of people's favorite papers from 2025, so I made a list of 16 #lipidtime studies from 2025 that I found interesting. Here they are in no particular order (please add more if you would like!), and here's to much more exciting science in 2026! 🧪
- Reposted by Levental LabRegensburg is a lovely place and a great Uni!
- A new year brings new opportunities: we are looking to fill a permanent professorship position with a Microbiologist preferably with expertise on archaeal biology, RNA biology or imaging techniques to unravel cell biology in prokaryotes! Please share and/or apply :)! www.nature.com/naturecareer...
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- Reposted by Levental LabProximity labeling users: check out this study by @zhixingchen2.bsky.social and Peng Zou, which establishes how much contact-dependence vs. diffusion is responsible for biotinylation — tl;dr TurboID has a much smaller effective radius! www.nature.com/articles/s41... 1/2
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- Reposted by Levental LabMapping cellular targets of covalent cancer drugs in the entire mammalian body: Cell www.cell.com/cell/fulltex...
- Reposted by Levental LabHappy to announce the publication of our foray into studying what happens to the transcriptomes of nuclei when cells fuse to form a syncytium. More to follow in the coming few years. One really wonderful thing about the Company of Biologists is that's it's free to publish there for my university!
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