Paper alert: Our study led by
@evapillai.bsky.social and
@sudimukherjee.bsky.social showing that mechanical properties of the
#brain actively shape the molecular landscape during development and
#axonpathfinding is finally out!
www.nature.com/articles/s41... @pdncambridge.bsky.social @fau.de @MPZPM

Long-range chemical signalling in vivo is regulated by mechanical signals - Nature Materials
Tissue stiffness mediated by Piezo1 is shown to regulate the expression of diffusive guidance cues in the developing Xenopus laevis brain, revealing a crosstalk between mechanical signals and long-ran...