Stefano Di Talia
Quantitative Developmental Biology @Duke
- Happy to have contributed, together with former student Yitong Xu, to this paper. Read the thread below from @brugueslab.bsky.social for more details.
- Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
- Reposted by Stefano Di TaliaExcited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
- Congrats, Ale and lab. A big step forward with a lot of new and unexpected observations! These waves are fascinating indeed
- The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj
- Reposted by Stefano Di TaliaAdvanced grad students + postdocs: apply for the 2026 #kitpqbio summer course, "Physical Principles of Morphogenesis in Plants and Animals," at buff.ly/OXXMKEv. Apply by Feb. 1. Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)
- @sushantbangru.bsky.social and @rdiegmiller.bsky.social new review on regeneration is out in Nature Reviews Molecular Cell Biology. A fun piece to write and another great collaboration with @kenposs.bsky.social.
- We are hiring!
- Please repost!!: We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!! www.nature.com/naturecareer...
- Just got back from a great visit to Vienna, spending time both at @impvienna.bsky.social and @istaresearch.bsky.social. Followed by a great visit to @embl.org. Amazing science, great and supportive colleagues and most notably incredible young trainees. It was so much fun to meet everyone.
- Thanks to @vdeneke.bsky.social , @pauligroup.bsky.social , @dianapinheiro.bsky.social , @ehannezo.bsky.social , @nicolettapetridou.bsky.social and Alexander Aulehla for hosting me.
- Always a treat to see Victoria and get updated about her science. Of course, she is always up to interesting and new stuff :)
- Thanks, Paul! Means a lot coming from you, as your papers have been great inspiration for this study
- Super impressive study by the group of Stefano di Talia on the segmentation of zebrafish notochord. There might even be a SNIC ! www.biorxiv.org/content/10.1...
- Reposted by Stefano Di Talia🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance
- 🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry. Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬 Register now ✍️ www.pasteur.fr/en/education...
- Reposted by Stefano Di TaliaTissue 'tectonic' collision is detrimental, but flies found two distinct solutions! Gratifying and grateful to be included in this collective effort, w/ Steffen Lemke, to crack the (or 'a') code of #cephalicfurrow, now out in @nature.com, all with @paveltomancak.bsky.social at the helm. (1/9)
- Priyom's preprint is out on biorxiv. See below for a detailed thread. In a nutshell, she has discovered and characterized the oscillator that times notochord and spine segmentation in zebrafish. Turns out that there are uniform Erk oscillations across the entire tissue that act as timekeepers!
- Building a spine is no joke, but thankfully zebrafish have their own clocks to keep the pace. Excited to share our preprint on the role of biological oscillators in coordinating notochord development! (www.biorxiv.org/content/10.1...) Additional thread below
- Reposted by Stefano Di TaliaBuilding a spine is no joke, but thankfully zebrafish have their own clocks to keep the pace. Excited to share our preprint on the role of biological oscillators in coordinating notochord development! (www.biorxiv.org/content/10.1...) Additional thread below
- Heartfelt obituary of Ben Shilo by Stas Shvartsman
- Reposted by Stefano Di TaliaJust noticed a super nice preview of our paper by @ditalialab.bsky.social and Alexandra Hiestand. As always, good editorial experience with @cp-cellsystems.bsky.social www.cell.com/cell-systems...
- Excited to share our paper on deciphering the design & control principles of tissue scaling w/ Luisa Arispe! Amazing work by co-first authors Danielle Pi and Jonas Braun. We show *differentiated* endothelial cell proliferate in waves with ultrafast cell cycle time of ~5h www.cell.com/cell-systems...
- Great dinner with current and former members of the lab, as well as current and former Duke members and friends of the lab. Great to catch up with @ceriweber.bsky.social ,Ben, @woonyunghur.bsky.social and share stories. Great @socdevbio.bsky.social meeting!
- Excited to see @drsusanna.bsky.social 's work out as a preprint. Please read the thread below for some more information or check the paper out on biorxiv. www.biorxiv.org/content/10.1...
- Excited to share the bulk of my postdocotoral work from the @ditalialab.bsky.social on how cells interpret dynamic morphogen signaling during development! Many thanks to our collaborators & coauthors @shelbyflies.bsky.social, Massimo Vergassola, Jacqueline Janssen, and Anna Chao.
- Reposted by Stefano Di TaliaA heartfelt thank you to @izfs.bsky.social for this incredible honor! I'm so grateful to receive an award in memory of Dr. Chi-Bin Chien, an inspiring scientist and pioneer in the zebrafish community 🐟💙
- We are excited to announce the winner of the Chi-Bin Chien Award, Dr. Victoria Deneke! See more about Dr. Deneke and the CBC Award here: www.izfs.org/news/congrat... @impvienna.bsky.social @vdeneke.bsky.social
- Very much looking forward to this meeting!
- 🔈 We’re pleased to welcome Stefano Di Talia @ditalialab.bsky.social as an invited speaker at #ICDB2025! His work combines imaging and quantitative models to understand cell cycle coordination during embryonic development. 📊🧪
- Highly recommended! A great lab and wonderful mentor.
- 👩🔬Curious about #fertilisation and #development? Join Andrea Pauli’s group through the Vienna BioCenter #PhD Program! ⏳Deadline: 15 April training.vbc.ac.at/phd-program/ 📽️Watch Andi's 'Scientist Snapshot': www.youtube.com/watch?v=X9FN... @pauligroup.bsky.social
- Nice News & Views on our recent paper from Tim Saunders. www.nature.com/articles/s41...
- Reposted by Stefano Di TaliaWe are hiring! Interested in X chromosome inactivation, cell biology, and epigenetics? Funded postdoctoral position in our lab at the Koç University Mol Bio and Genetics Department, in Istanbul Türkiye. DM for more details.
- Our paper, led by @argo-mkhrji.bsky.social and @woonyunghur.bsky.social, on cortical migration of nuclei in drosophila embryos came out today in @naturephysics.bsky.social. Argo wrote a comprehensive thread below. A great collaboration with Massimo Vergassola and @streichan.bsky.social.
- 1/n Wanted to share this latest piece of work that came online today on how Scale-independent and Topological interactions govern the spindle orientation and in turn the decision to become embryonic/yolk nuclei. Freely available to read here: rdcu.be/ebb0l
- Also thanks to the @kitp-ucsb.bsky.social for supporting Woon during his stay in Santa Barbara to perform a lot of the work that went into the paper
- Great new paper on spatiotemporal organization of cell division in zebrafish embryos. The mitotic waves preceding the ZGA are phase waves set by differences in N/C ratio, driven by geometry-induced asymmetric divisions. Important new insights and very interesting addition to the field.
- 📢‼️ Exciting new preprint from the lab by @nikhil-mishra.bsky.social et al, now out on @biorxivpreprint.bsky.social, reveals that the early embryo geometry spatiotemporally patterns zygotic genome activation (ZGA) in zebrafish. 🐟 tinyurl.com/Biorxiv-nmis... Read on to learn more... 👇
- What an awesome paper from Olga showing how in zebrafish the scaling of anaphase movements is controlled by cytoplasmic flows! Love to see a new role for cytoplasmic flows ;) and excited to learn that scaling of anaphase is controlled so differently in fly and fish embryos.
- Very nice dispatch describing Yitong's paper from Akihiro Tanaka and Yuta Shimamoto. www.cell.com/current-biol...
- Ashley's postdoc work is now posted on bioRxiv. www.biorxiv.org/content/10.1...
- Here we asked how the memory of bone size is encoded during zebrafish regeneration. This process nicely illustrates the concept of positional (geometric) memory, that is the ability of the regenerating fin to grow back to its pre-injury size and shape.
- Using quantitative approaches, we first demonstrated the tissue growth is mainly controlled by the proliferation of existing osteoblasts.
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View full threadCollectively, our work leads to a new paradigm for the control of positional memory during regeneration. The Fgf20a source encodes the amount of tissue removed and controls a cellular program that ensures the decay and scaled expansion of Erk gradients which in turn control tissue growth
- Reposted by Stefano Di Talia📣 Excited to receive the 💥 NSF CAREER 💥 Award. Our group is looking for PhD students and postdocs interested in the Nonlinear Dynamics and the Physics of Living Systems, with support from NSF, HFSP, and other sources. We’d appreciate your help in spreading the word! @ucsdphysci.bsky.social
- Reposted by Stefano Di TaliaJoin us next week for another western/evening 🌙 session seminar! Our speakers will be: Stefano Di Talia @ditalialab.bsky.social and Chaitanya Dingare 🗓️ Thursday, January 23rd at ⏰ 09:30 PST / 12:30 EST / 17:30 UTC / 17:30 GMT / 18:30 CET
- Reposted by Stefano Di TaliaHow did microtubules adapt to support life across 🐸 species at divergent thermal niches? Now online & OA @currentbiology.bsky.social Thanks to Ella, Luca, @biswashere.bsky.social & Carolyn @mpiib-berlin.mpg.de @BirkbeckUoL 🙌 Enjoy reading! 👉 www.cell.com/current-biol...
